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Nascent chromatin structure and the response to DNA damage during replication

Nascent chromatin structure and the response to DNA damage during replication
新生染色质结构和复制过程中对 DNA 损伤的反应
批准号：
252771
负责人：
Wurtele Hugo
金额：
$42.34万
依托单位：
CIUSSS Est-de-l'Ile-de- Montral-Maisonneuve Rosemont
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-03-01 至 2017-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=252771&lang=en
关键词：
Chromatin Dna Repair Dna Replication Fluorescence Microscopy Genetic Interactions Histone Modification Homologous Recombination Ubiquitination

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中文摘要
翻译
DNA损伤会导致重要基因失活或调控不当，从而导致癌症。幸运的是，细胞拥有DNA修复机制，使它们能够在DNA损伤(如DNA断裂)存在的情况下存活。然而，这些修复机械
英文摘要
DNA damage can lead to the inactivation or misregulation of important genes and cause cancer. Fortunately, cells possess DNA repair mechanisms that allow them to survive in the presence of DNA lesions such as breaks in the DNA. However, these repair mecha
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Nascent chromatin structure and the response to DNA damage during replication
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