US-UK Cooperative Research: Evolutionary Biology of Parasite-Host Interactions

该奖项将支持系统性的合作研究， 科罗拉多州立大学的Janice摩尔博士 和两位英国科学家：保罗·哈维博士， 牛津大学动物学和DWT博士克朗普顿， 格拉斯哥大学动物学系。 客观 这项研究的一个重点是发展和使用系统发育技术， 研究宿主进化在寄生-宿主关系中的作用 交互. 寄生物-宿主相互作用的进化已经被探讨 从宿主利益的角度来看（例如， 寄生虫）和寄生虫益处（例如操纵宿主 行为），但尚未从系统发育 perspective. 在一组严格可比的行为 实验中，摩尔博士目前正在研究的影响， 棘头虫，念珠形，对十个行为的影响 与蟑螂有关的物种。 在长期的研究中， 访问牛津大学，摩尔博士将扩大分析 技术发展到那里的主机寄生虫现象， 将研究寄生虫中宿主生殖的作用- 诱发行为改变 在随后的研究中， 留在格拉斯哥大学，摩尔博士将量化 对寄生虫表现出的抗性程度， 宿主物种，并应用相同的技术来阐明 如果有的话，宿主的寄生性对寄生虫抗性的贡献。 在这个研究年里，摩尔博士将能够与 进化生物学领域的主要人物， 行为学、寄生虫生态学和寄生虫抗性， 扩展免费开发的比较分析技术- 宿主-寄生虫相互作用的生物分类群。 这将是 第一个量化的步骤，把这些现象在一个 预测性的进化框架

This award will support collaborative research in systematic biology between Dr. Janice Moore, Colorado State University and two British scientists: Dr. Paul Harvey, Department of Zoology, University of Oxford, and Dr. D.W.T. Crompton, Department of Zoology, University of Glasgow. The objective of the research is to develop and use phylogenetic techniques to examine the role of host evolution in parasite-host interactions. The evolution of parasite-host interactions has been approached from the standpoint of host benefit (e.g. resistance to parasites) and parasite benefit (e.g. manipulation of host behavior), but has not been addressed from a phylogenetic perspective. In a set of strictly comparable behavioral experiments, Dr. Moore is currently examining the effect of the acanthocephalan, Moniliformis, on the behavior of ten species of related cockroaches. During a long term research visit at Oxford University, Dr Moore will extend analytical techniques developed there to host-parasite phenomena and will investigate the role of host phylogeny in parasite- induced behavioral alterations. During a subsequent research stay at the University of Glasgow, Dr. Moore will quantify degrees of resistance to the parasite exhibited by these same host species and apply the same techniques to elucidate the contribution, if any, of host phylogeny to parasite resistance. During this research year, Dr. Moore will be able to interact with major figures in the area of evolutionary biology, ethology, parasite ecology and parasite resistance, and to extend comparative analytical techniques developed for free- living taxa to host-parasite interactions. This will be the first quantitative step towards placing these phenomena in a predictive, evolutionary frame.