Investigating INPP4B signalling as a target for therapy in leukaemia
Investigating INPP4B signalling as a target for therapy in leukaemia
批准号:
380561
负责人:
Salmena Leonardo L
金额:
$54.34万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-03-01 至 2023-03-01
中文摘要
AML是一种侵袭性白血病,依赖于LSCs(白血病干细胞)细胞的功能。临床医生认为,只有完全清除LSCs,白血病才能治愈。我们的研究小组发现AML患者具有高
英文摘要
AML is an aggressive type of leukemia that depends on the function of cells called LSCs (leukemia stem cells). Clinicians believe that leukemia can be cured only when LSCs are completely eliminated. Our research group identified that AML patients with hig
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会议论文
Investigating a novel phosphoinositide-lysosomal signalling axis for pancreatic cancer therapy
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批准号:477270
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项目类别:Operating Grants
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资助金额:$7.29万
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财政年份:2022
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负责人:Salmena Leonardo L
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依托单位:
Identification and characterization of microRNAs essential for the development and fitness of chemoresistant AML
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批准号:433601
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项目类别:Operating Grants
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资助金额:$65.48万
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财政年份:2020
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负责人:Salmena Leonardo L
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依托单位:
Canada Research Chair - Tier 2
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批准号:415492
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项目类别:
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资助金额:$36.43万
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财政年份:2019
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负责人:Salmena Leonardo L
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依托单位:
Investigating the novel stem cell function of the phosphoinositide phosphatase INPP4B in hematopoiesis and leukemia
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批准号:351773
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项目类别:Operating Grants
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资助金额:$7.29万
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财政年份:2016
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负责人:Salmena Leonardo L
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依托单位:
Canada Research Chair Tier 2
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批准号:315508
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项目类别:
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资助金额:$36.43万
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财政年份:2014
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负责人:Salmena Leonardo L
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依托单位:
海外基金