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Mechanistic studies of cell-free DNA and histones in sepsis: At the interface of innate immunity, coagulation, and inflammation

Mechanistic studies of cell-free DNA and histones in sepsis: At the interface of innate immunity, coagulation, and inflammation
脓毒症中游离 DNA 和组蛋白的机制研究:先天免疫、凝血和炎症的界面
批准号:
379803
负责人:
Liaw Patricia C
金额:
$39.85万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-03-01 至 2023-03-01

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中文摘要
翻译
脓毒症(即。血液中毒是由血液或组织中的有害微生物或其毒素引起的。这些有害物质会导致血液凝块形成和炎症的恶性循环,这可能导致多器官衰竭甚至死亡
英文摘要
Sepsis (ie. blood poisoning) is triggered by harmful microorganisms or their toxins in the blood or tissues. These harmful agents can cause a vicious cycle of blood clot formation and inflammation, which may lead to multiple organ failure and death even a
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会议论文
Translational studies of heparin in sepsis-associated immunothrombosis
  • 批准号:
    478457
  • 项目类别:
    Operating Grants
  • 资助金额:
    $47.77万
  • 财政年份:
    2023
  • 负责人:
    Liaw Patricia C
  • 依托单位:
Intravenous DNase I for the treatment of sepsis: A phase 1 safety and feasibility study in ICU patients
  • 批准号:
    451591
  • 项目类别:
    Operating Grants
  • 资助金额:
    $28.98万
  • 财政年份:
    2021
  • 负责人:
    Liaw Patricia C
  • 依托单位:
Mechanisms by which by cell-free DNA modulates coagulation and inflammation
  • 批准号:
    306353
  • 项目类别:
    Operating Grants
  • 资助金额:
    $31.47万
  • 财政年份:
    2014
  • 负责人:
    Liaw Patricia C
  • 依托单位:
Studies of plasma DNA in sepsis
  • 批准号:
    200141
  • 项目类别:
    Operating Grants
  • 资助金额:
    $57.85万
  • 财政年份:
    2010
  • 负责人:
    Liaw Patricia C
  • 依托单位:
海外基金