Molecular and Demographic Population Genetic Studies of Southwestern Indian Tribes

该项目的主要目标是澄清 一些美国西南部的进化关系 印第安部落通过分析采集的血样 通过阿尔伯克基印第安人医院 遗传 这些部落的关系一直是争论的根源， 多年 随着DNA分型技术的发展， 现在可以估计的遗传相关性的 人口比以前精确得多。 作为 语言学家还开发了衡量语言差异的方法 对于这些部落来说， 根据遗传学判断的亲缘关系树和 语言标准。 将对15个种群进行抽样，并对100多个种群进行分类。 多态位点 数学模型考虑到 这两种相似性都是由于来自共同祖先的血统， 由于迁移和混合，将使用。

The primary objective of this project is to clarify the evolutionary relationships of a number of Southwestern American Indian tribes through the analysis of blood samples gathered through the Albuquerque Indian Hospital. The genetic relationships of these tribes have been a source of debate for many years. With the development of DNA typing techniques, it is now possible to estimate the genetic relatedness of the populations with much greater precision than previously. As linguists have also developed measures of linguistic divergence for the tribes, it will be possible to measure the similarities between the trees of relatedness as judged by genetic and linguistic criteria. Fifteen populations will be sampled and typings done on over 100 polymorphic loci. Mathematical models which take into account both similarities due to descent from a common ancestor and those due to migration and admixture will be employed.