Phytochrome: Biogenesis and Molecular Properties

研究的具体目标是确定序列， 光敏色素A分子的结构特征， 监管行动。 在此期间，重点使用 突变光敏色素A在转基因植物中的过度表达 拟南芥，以确定功能上重要的残基。 这 重点将利用最近开发的转基因 拟南芥系统，提供了一个容易scorable下胚轴 突变体中功能丧失的长度表型 多肽。 %%% 这项研究的意义在于，它将有助于定义 调节主开关，光敏色素， 控制植物基因对光照的反应。

The specific objective for the research is to identify sequence and structural features of the phytochrome A molecule involved in its regulatory action. During this period the focus on the use of overexpreession of mutagenized phytochrome A in trangenic Arabidopsis to identify functionally important residues. This focus will capitalize on the recently developed transgenic Arabidopsis system which provides an easily scorable hypocotyl length phenotype for loss of function in the mutagenized polypeptide. %%% The significance of this research is that it will help define the mechanism by which the regulatory master switch, phytochrome, controls plant gene expression in response to light.