Conference of the NYAS: The Melanotropic Peptides; Sept. 6-9, 1992; Rouen, France

提供资金，以帮助支付参加者和年轻科学家参加国际会议的费用，对嗜黑肽。促黑素（Melanotropins， MSH, melanin- concentration hormone， MCH）是最早进行结构分析和化学合成的肽之一。虽然它们对色素沉着的生物学作用，特别是在无脊椎动物物种中，已被广泛认识，但很明显，促黑素影响中枢神经系统和特定的外周器官。本次会议将讨论这些肽的生物合成、分泌和分子作用机制方面的重要进展。它涵盖了从MSH的发现到其作为神经肽作用的最新知识的所有主题。会议的形式为跨学科的科学家群体之间的有意义的交流提供了氛围。最后的讨论将推测基础研究的这些快速进展如何可能导致促黑素蛋白在黑色素瘤的诊断和治疗、色素紊乱、神经损伤和痴呆中的潜在临床应用。

Funds are provided to help defray costs for participants and young scientists to attend an International Conference on Melanotropic Peptides. Melanotropins, (melanocyte-stimulating hormones, MSH; melanin-concentrating hormone, MCH) were among the first peptides to be structurally analyzed and to be chemically synthesized. While their biological effects on pigmentation, especially in invertebrate species, have been widely appreciated, it is clear that melanotropins affect the central nervous system and specific peripheral organs. This conference will address the important advances being made on the biosynthesis, secretion and molecular mechanisms of action of these peptides. It covers the full spectrum of topics from the discovery of MSH to most current knowledge of its role as neuropeptides. The conference's format provides the atmosphere to foster meaningful interchanges between an interdisciplinary group of scientists. The final discussion will speculate on how these rapid advances in basic research may lead to the potential clinical use of melanotropins in the diagnosis and therapy of melanoma, the treatment of pigment disorders, nerve damage and dementia.