Investigation of microbiome-aryl hydrocarbon receptor crosstalk and immune suppression in pancreatic cancer
Investigation of microbiome-aryl hydrocarbon receptor crosstalk and immune suppression in pancreatic cancer
批准号:
418937
负责人:
McGaha Tracy
金额:
$74.12万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
未结题
起止时间:
2020-03-01 至 2025-03-01
中文摘要
胰腺癌是最致命的癌症之一,5年生存率为7%。我们的初步数据表明,驱动胰腺肿瘤进展的一个关键因素是肠道微生物组产生的met驱动肿瘤的深刻免疫抑制
英文摘要
Pancreatic cancer is one of the most lethal forms of cancer with 5-year survival rates of 7%. Our preliminary data suggest a key factor driving pancreatic tumor progression is the profound immune suppression in tumors driven by gut microbiome-produced met
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会议论文
Mechanistic studies of macrophages and the tumour microenvironment as immunologic barriers to therapy in pancreatic ductal adenocarcinoma
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批准号:387747
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项目类别:Operating Grants
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资助金额:$77.19万
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财政年份:2018
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负责人:McGaha Tracy
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依托单位: