A Fourier Transform NMR Spectrometer for Undergraduate Use

化学系正在购买一台200 MHz的FT-NMR光谱仪，带有1H/ 13C探针，可变温度能力和样品转换器。核磁共振的使用已被纳入本科四年的化学课程，从一年级的荣誉课程开始，到两门新的高级课程结束。其中一门课程涉及无机和有机合成方法。学生项目包括跟踪金属催化的环加成反应活性位点的演变，从而使学生熟悉合成-表征-设计/再设计循环的过程，这对解决化学合成中的问题很重要。第二门新开设的高级课程强调傅里叶变换核磁共振光谱的原理和核磁共振更高级的实验室应用，包括命令操作模式、光谱优化、DEPT、选择性同核解耦、溶剂抑制、多重量子滤波的COSY和其他先进的二维实验。样品交换器允许学生注册在入门有机化学实验室获得他们的反应产物的常规核磁共振光谱。

The Department of Chemistry is purchasing a 200 MHz FT-NMR spectrometer with a 1H/ 13C probe, variable temperature capabilities, and a sample changer. The use of nmr is being incorporated into all four years of the undergraduate chemistry curriculum beginning with the freshmen honors course and culminating with two new senior-level courses. One of these courses involves inorganic and organic approaches to synthesis. Student projects include following the evolution of the active site of a metal-catalyzed cycloaddition reaction, thus familiarizing students with the process of synthesis- characterization-design/redesign cycle important to solving problems in chemical synthesis. The second new senior-level course emphasizes the principles of fourier transform NMR spectroscopy and more advanced laboratory applications of NMR including, command mode of operation, spectral optimization, DEPT, selective homonuclear decoupling, solvent suppression, multiple quantum filtered COSY and other advanced two- dimensional experiments. The sample changer allows students enrolled in the introductory organic chemistry laboratory to obtain routine NMR spectra of their reaction products.