Investigating interdependencies between epigenetic modifications: towards combinatorial epigenetic cancer therapeutics
Investigating interdependencies between epigenetic modifications: towards combinatorial epigenetic cancer therapeutics
批准号:
461707
负责人:
Majewski Jacek A
金额:
$61.58万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-03-01 至 2027-03-01
中文摘要
虽然单个生物体中的所有细胞都含有几乎相同的DNA,但每种细胞类型和组织都具有不同的特性。这些特性是由许多“表观遗传”修饰决定的,如组蛋白和DNA甲基化,这些修饰决定了基因的功能。
英文摘要
While all cells within an individual organism contain nearly identical DNA, each cell type and tissue has distinct properties. Those properties are determined by a number of "epigenetic" modifications, such as histone and DNA methylation, which dictate wh
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会议论文
Splicing Defects in Human Hereditary Disease
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批准号:321849
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项目类别:Operating Grants
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资助金额:$38.5万
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财政年份:2015
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负责人:Majewski Jacek A
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依托单位:
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负责人:Majewski Jacek A
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依托单位:
CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
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批准号:216091
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项目类别:
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资助金额:$36.43万
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财政年份:2009
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负责人:Majewski Jacek A
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依托单位:
海外基金