Investigating the role of the T4 secretion system in the pathogenesis of Crohn's disease-associated bacteria
Investigating the role of the T4 secretion system in the pathogenesis of Crohn's disease-associated bacteria
批准号:
486606
负责人:
Asrar Tahreem
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-12-01 至 2023-12-01
中文摘要
克罗恩病(CD)是由对微生物组的免疫反应失调引起的。粘附-侵袭性大肠杆菌(AIEC)菌株已知可驱动肠道炎症,但其潜在机制尚不清楚。我们最近为这种类型确定了一个角色
英文摘要
Crohn's disease (CD) is caused by a dysregulated immune response to the microbiome. Adherent-invasive Escherichia coli (AIEC) strains are known to drive gut inflammation, yet the underlying mechanisms are unknown. We recently identified a role for the typ
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