Protein Monolayer Electrochemistry

这个分析和表面化学领域的项目涉及界面蛋白质电化学的研究。这是一笔新的拨款，将把鲍登教授的研究计划扩展到涂有有机硫酸盐自组装单分子膜的金电极上电子传递机制的基础研究领域。其目的是加深我们对生物系统中远程电子转移过程的理解。建议研究的吸附蛋白质将作为蛋白质/蛋白质复合体的电化学类似物。因此，实验结果将有助于阐明酶与电子导电材料之间的电子耦合机理。鲍登教授和他的学生将使用电化学和光谱技术来研究生物电子传递过程，电极上覆盖着一层有机材料的薄膜。这项研究的目的是对生物系统中的蛋白质/蛋白质相互作用进行建模。研究结果将对新型生物探针和传感器的设计具有一定的参考价值。

This project in the area of analytical and surface chemistry involves the study of interfacial protein electrochemistry. It is a renewal grant which will extend Professor Bowden's research program into the area of fundamental investigations of electron transfer mechanisms on gold electrodes coated with organothiolate self-assembled monolayer films. The goal is to further our understanding of long-range electron transfer processes in biological systems. The adsorbed proteins proposed for study will serve as the electrochemical analogs of protein/protein compexes. Thus, the experimental results will help to elucidate electronic coupling mechanisms between enzymes and electronically conducting materials. %%% Professor Bowden and his students will use both electrochemical and spectroscopic techniques to study biological electron transfer processes with electrodes coated with a thin film of organic material. The objective of the research is to model protein/protein interactions in biological systems. The results will be of value for the design of new biological probes and sensors.