Dissertation Research: The Impact of Perceived Stress, Health Behavior, and Social Support on the Occurrence of IBD in Asian and British Populations in Great Britain

人们普遍认为，心理社会压力与健康有因果关系，但这种关系的确切性质尚不清楚。本研究的目的是检验社会因素的重要性，特别是社会支持和文化决定的健康相关行为差异，作为联系心理社会压力和健康结果的干预变量。特别地，心理社会压力、社会支持与病态炎症性肠病（IBD）发作的频率、持续时间和严重程度之间的相互关系将在英国两个城市的亚洲和英国居民中进行研究。IBD是一类病因不明的慢性胃肠道疾病，可引起恶心、疼痛和血性腹泻。一般来说，欧洲，尤其是英国，是世界上IBD患病率最高的地区，这表明欧洲血统的人有遗传易感性。然而，生活在英国的亚洲人表现出与英国本地人相似的IBD患病率。亚洲人和英国本地人都表现出IBD的高患病率，这一事实表明，非遗传因素在IBD的病因学中起着重要作用，这些因素对英国的英国人和亚洲居民的影响相同。心理社会压力与疾病的发生和复发有关。英国莱斯特的试点研究表明，在感知压力和健康行为方面的文化差异会影响IBD发作的频率、持续时间和严重程度，这些差异被患病率所掩盖。本研究的假设是，英国人和亚洲人在识别和通过行为应对压力情况方面具有不同的文化模式，从而导致不同的健康模式和与压力相关的慢性疾病，在本研究中是IBD。人们普遍认为，心理社会压力与健康有因果关系，但这种关系的确切性质尚不清楚%’!!!F S Times New Roman Symbol & Arial 1 press Elite 5 Courier New & Casablanca q ' h 2 E 2 E + 2 DEBRA TERESA WHITE Raymond Hames

McGrath/Barone 9309267 It is generally accepted that psycho social stress is causally related to health but the precise nature of this relationship is not clear. The purpose of the present study is to examine the importance of social factors, particularly social support and culturally determined differences in health-related behaviors, as intervening variables linking psycho social stress and health outcome. In particular, the interrelationships between psycho social stress, social support, and the frequency, duration, and severity of morbid Inflammatory Bowel Disease (IBD) episodes will be examined in Asian and British residents of two cities in Great Britain. IBD is a category of chronic gastrointestinal tract diseases, of unknown etiology, that produces episodes of nausea, pain and bloody diarrhea. Europe in general and Great Britain in particular are known to have the highest worldwide prevalences of IBD, suggesting a genetic predisposition for people of European ancestry. However, Asians living in Great Britain exhibit prevalences of IBD similar to native Britons. The fact that both Asians and native Britons exhibit high prevalences of IBD suggests that non genetic factors play an important role in the etiology of IBD and that these factors impact equally on British and Asian residents of Great Britain. Psycho social stress is associated with disease onset and recurrence by physicians and patients. Pilot research in Leicester, England suggests cultural differences in perceived stress and health behavior affect the frequency, duration, and severity of IBD episodes, differences masked in prevalence rat es. It is the hypothesis of the present study that British and Asian populations have different cultural patterns for identifying and responding through behavior to stressful situations, resulting in different patterns of health and stress-related chronic disease, in this case IBD. *** McGrath/Barone It is generally accepted that psycholsocial stress is causally related to health but the precise nature of thi % ' ! ! ! F S Times New Roman Symbol & Arial 1 Pres Elite 5 Courier New & Casablanca q " h 2 E 2 E + 2 DEBRA TERESA WHITE Raymond Hames