A Central Shared Computer Resource for Molecular and Cellular Biology

9318128 Smith本提案的目的是筹集资金，将我们的VAX 6000-410计算机升级到DEC 7000-610，通过增加新的SCSI磁盘来增加我们的磁盘空间，购买光纤集线器设备，允许新计算机直接连接到医疗中心的光纤网络，并增加两个新的x终端和一个彩色打印机供公众使用。这台计算机目前作为医疗中心的共享中心资源，为医疗中心几乎所有从事分子生物学研究的科学家提供数据库存储和计算能力。当前的机器被快速增长的用户数量和快速增长的分子生物学数据库所淹没。此外，除了为大量需要基本计算设施的同行评审和资助项目提供服务外，还需要为选择购买高性能macintosh、ibm - pc和工作站的快速增长的用户提供文件和计算服务器。我们共享资源的目标是加强现有服务和提供新设施，其中一些正在医疗中心开发中。这些资源包括新的数据库，用于分析分子结构的工具，以及选定的图像处理工具和资源。我们的目标是支持从分子到细胞各个层面的生物结构研究。PI和copi目前是——并将继续是——计算机系统的主要用户。他们共同致力于共享计算资源，并参与将提高其对医疗中心和更广泛的国际研究界的价值的项目。

9318128 Smith The purpose of this proposal is to generate funds to upgrade our VAX 6000-410 computer to a DEC 7000-610, to increase our disk space by adding new SCSI disks, to purchase fiber-optic hub equipment allowing the new computer to be connected directly to the Medical Center's fiber-optic network, and to add two new X-terminals and a color printer for public use. The computer currently functions as a shared central resource within the Medical Center providing data bank storage and computing power for nearly all research scientists at the Medical Center whose work involves molecular biology. The current machine is overwhelmed by the rapidly increasing number of users, and the rapid growth of the molecular biology databases. Additionally, the resource is required to fill an expanding role as a file and compute server for a rapidly growing number of users who are choosing to purchase high power Macintoshes, IBM-PCs and workstations, in addition to serving a large group of peer reviewed and funded projects requiring basic computing facilities. The goal of our shared resource is to enhance current services and to provide new facilities, some of which are under development in the Medical Center. These resources consist of new databases, tools for the analysis of molecular structure, and selected image processing tools and resources. Our goal is to support research on biological structure at all levels from the molecular to the cellular. The PI and the CoPIs are currently--and will continue to be- -major users of the computer system. They share a commitment to a shared computing resource and are involved in projects that will enhance its value to the Medical Center and the broader international research community.