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Role of the Nervus Terminalis in Chemoreception and Behavior

Role of the Nervus Terminalis in Chemoreception and Behavior
终末神经在化学感受和行为中的作用
批准号:
9320350
负责人:
Celeste Wirsig-Wiechmann
金额:
$1.88万
依托单位国家:
美国
项目类别:
Continuing grant
财政年份:
1994
资助国家:
美国
项目状态:
已结题
起止时间:
1994-06-15 至 1995-05-31

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中文摘要
翻译
感觉、运动和神经内分泌系统的协调对许多物种的生存至关重要。事实上,两种鼻腔化学感觉系统,嗅觉系统和犁鼻系统,在许多脊椎动物的生殖活动中起着重要作用。末梢神经是鼻腔中的另一个神经系统。然而,与嗅觉系统和犁鼻系统不同的是,人们对这种脑神经的功能知之甚少。wirsigg - wiechmann博士已经证明,这种延伸到大脑的神经复合体含有促性腺激素释放激素,一种调节生殖许多方面的激素。使用比较方法结合各种最先进的解剖学技术,她将确定神经末梢的神经解剖学组织和该激素受体的相应分布。为了检查它的功能,wirsigg - wiechmann博士将检查激活末梢神经神经元基因表达的感觉和行为条件。这些研究的结果将更好地定义感觉、神经激素和行为系统之间的相互关系。这可能会让我们更彻底地了解动物环境是如何影响对生存至关重要的生殖能力的。***
英文摘要
9320250 Wirsig-Wiechmann Coordination of sensory, motor and neuroendocrine systems is essential for survival of many species. Indeed two nasal chemosensory systems, the olfactory and vomeronasal systems, are known to play a significant role in reproductive activities of many vertebrates species. The nervus terminalis is another neural system in the nasal cavity. Unlike the olfactory and vomeronasal systems, however, little is known about the function of this cranial nerve. Dr. Wirsig-Wiechmann has shown that this neural complex which extends into the brain contains gonadotropin-releasing hormone, a hormone mediating many aspects of reproduction. Using a comparative approach combined with a variety of state-of-the-art anatomical techniques, she will determine the neuroanatomical organization of the nervus terminalis and the corresponding distribution of receptors for this hormone. To examine its function, Dr. Wirsig-Wiechmann will examine sensory and behavioral conditions that activate gene expression in nervus terminalis neurons. The results of these studies will better define the interrelationship between sensory, neurohormonal and behavioral systems. It may lead to a more thorough understanding of how the animals environment affects its reproductive capabilities that are important for survival. ***
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CAREER: Molecular Biology of the Terminal Nerve System
Role of the Nervus Terminalis in Chemoreception and Behavior
Role of the Nervus Terminalis in Chemoreception and Behavior
  • 批准号:
    9496258
  • 项目类别:
    Continuing grant
  • 资助金额:
    $22.33万
  • 财政年份:
    1994
  • 负责人:
    Celeste Wirsig-Wiechmann
  • 依托单位:
海外基金