Mouse Mutant Stocks Center

9502221 Davisson这一奖项重申了美国国家科学基金会对杰克逊实验室小鼠突变体库中心(MMSC)的支持，杰克逊实验室是国际知名的实验室小鼠遗传学研究中心。小鼠是研究哺乳动物遗传和发育各个方面的主要实验系统。MMSC有两个任务：1)维护和分发突变小鼠的品系和有关品系的信息给科学界，2)发现和表征小鼠的新的自发突变。在小鼠中检测到大约950个自发突变；其中121个突变由MMSC维持的库存代表。此外，杰克逊实验室保存的大量具有良好遗传特征的繁育小鼠群体是新的自发突变的一个特别方便和廉价的来源。每年，NSF对这一收集的支持都会使大量学术、非营利、政府和工业研究人员受益，他们要求获得已知或新检测到的突变。***

9502221 Davisson This award renews NSF support of the Mouse Mutant Stocks Center (MMSC) at The Jackson Laboratory, an internationally renowned center for genetic studies of the laboratory mouse. The mouse is the primary experimental system for study of a variety of aspects of mammalian genetics and development. The MMSC has two missions: 1) to maintain and distribute strains of mutant mice and information about the strains to the scientific community, and 2) discover and characterize new spontaneous mutations in the mouse. Approximately 950 spontaneous mutations have been detected in the mouse; of these, 121 mutations are represented by the stocks maintained by the MMSC. In addition, the large breeding colonies of genetically well-characterized mice maintained at The Jackson Laboratory are a particularly convenient and inexpensive source of new spontaneous mutations. Each year, the NSF support for this collection benefits a large number of academic, non-profit, government and industrial researchers who request with known or newly detected mutations. ***