Synthetic Applications of Hypervalent Iodonium Ylides

本研究的重点是使用高价碘试剂， 合成. 碘叶立德将用于影响对映选择性 分子内环丙烷化、氮丙啶化和产生高 能量碳阳离子当量。 含I-I键的碘鎓叶立德 由于对碘-碘共轭的兴趣， 与导电有机分子的连接。 最后运用 钯催化碳碳键中的高价碘底物 形成反应。 有了这个奖项，合成有机计划正在支持这项研究 罗伯特·M博士化学系的莫里亚蒂说， 伊利诺伊大学芝加哥分校。 莫里亚蒂博士将把工作重点放在 高价碘试剂在有机合成中的应用。 高价碘化合物形成一类对环境安全， 可用于多种有用的合成的通用试剂 转变

The focus of this research is the use of hypervalent iodine reagents in synthesis. Iodonium ylides will be used to affect enantioselective intramolecular cyclopropanation, aziridination and the generation of high energy carbocation equivalents. Iodonium ylides containing I-I bonds will be synthesized because of interest in iodine-iodine conjugation in connection with conducting organic molecules. Finally, the use of hypervalent iodine substrates in palladium catalysed carbon-carbon bond forming reactions will be persued. With this award, the Synthetic Organic Program is supporting the research of Dr. Robert M. Moriarty of the Department of Chemistry at the University of Illinois at Chicago. Dr. Moriarty will focus his work on the use of hypervalent iodine reagents in organic synthesis. Hypervalent iodine compounds form a class of environmentally safe, versatile reagents which can be used in a variety of useful synthetic transformations.