SBIR PHASE I: The Development of a 600 MHz Wide Bore (89mm) High Resolution NMR Magnet with Internal Tin Wires

本小企业创新研究一期项目是研究600MHz宽孔径（89mm）内锡超导导线高分辨率核磁共振磁体研制的可行性。用内部锡线代替青铜加工线，将大大降低高场核磁共振系统的成本。第一阶段的研究目标是解决内部锡线高场核磁共振磁体结构的工程问题。为了实现这一目标，cryomigtics公司将开发模型线圈，以实验方式确定内部锡线在持久模式下的稳定性。第一阶段的研究将包括NbTi和Nb3Sn接头的制造，线圈应力分布分析，退火工艺优化，淬火保护电路设计以及内部锡线圈在持久模式下的稳定性评估。在第一阶段结束时，将完成全尺寸600 MHz宽孔核磁共振磁体的工程设计，该设计将成为第二阶段研究的起点，第二阶段研究将直接针对内部锡线的全尺寸核磁共振磁体的开发。第一阶段的预期结果是证明内部锡丝在持续模式操作下的稳定性，并将内部锡丝应用于高场核磁共振磁体。第一阶段开发的新技术将通过降低核磁共振系统成本产生巨大的商业机会。所提出的宽口径核磁共振磁体系统将是理想的微成像和体内光谱以及生物固态核磁共振光谱。该项目一期和二期的顺利完成，将使低价格、大口径、高磁场的核磁共振磁体进入市场。＊＊＊

*** 9561581 Wu This Small Business Innovation Research Phase I project is to study the feasibility of the development of a 600MHz wide bore (89mm) high resolution NMR magnet with internal tin superconducting wires. Replacing bronze-processed wire by internal tin wire, high field NMR system cost will be reduced significantly. The Phase I research objective is to solve engineering problems related to construction of high field NMR magnets with internal tin wire. To achieve the objectives, Cryomagnetics, Inc. will develop model coils to experimentally determine the internal tin wire stability in persistent mode operation. Phase I research will include fabrication of NbTi and Nb3Sn joints, analysis of stress distribution in the coils, optimization of the annealing process, design of quench protection circuits and evaluation of internal tin coil stability in persistent mode. At the end of Phase I, an engineering design of a full scale 600 MHz wide bore NMR magnet will be completed, and this design will be the starting point for Phase II research which will be directed toward development of a full scale NMR magnet with internal tin wire. The anticipated results from Phase I are to demonstrate the stability of internal tin wire in persistent mode operation and apply internal tin wire to high field NMR magnets. The new technologies developed in Phase I will generate great commercial opportunities by reducing NMR system costs. The proposed wide bore NMR magnet systems will be ideal for micro imaging and in vivo spectroscopy as well as biological solid state NMR spectroscopy. The successful completion of Phase I & II of this project will make low price, wide bore, high field NMR magnets available in the market. ***