Mechanisms of Alkene-Metal Oxide Interactions

这项研究的重点将涉及到以金属氧杂环己烷为基元的新Re化合物的制备。LReOn类型的化合物将是主要的合成目标，这些中间体将用于形成雷诺氧杂环烷。后者将作为理解烯烃环氧化和双羟基化反应机理的探针。还将对反应分子CP*ReO2的化学进行单独的研究。该分子从环氧化物中吸收氧，其机理可能与二羟基环还原有关。通过这个奖项，有机动态计划支持俄勒冈州立大学化学系的Kevin P.Gable博士的研究。盖博教授将专注于详细了解过渡金属氧化物介导的烯烃氧化过程中碳-氧键的形成。这类氧化反应是制备商品化学品和合成精细化学品的一类重要反应。

The focus of this research will involve the preparation of new rhenium compounds with the metallaoxetane motif. Compounds of the type LReOn will be the primary synthetic targets and these intermediates will be used to form rhenaoxetanes. The latter will serve as probes for the understanding of the mechanism of the epoxidation and the bishydroxylation of alkenes. A separate investigation of the chemistry of the reactive molecule Cp*ReO2 will also be undertaken. This molecule abstracts oxygen from epoxides and the mechanism of the process may be related to that for diolate cycloreversion. With this award, the Organic Dynamic Program is supporting the research of Dr. Kevin P. Gable of the Department of Chemistry at Oregon State University. Professor Gable will focus his work on developing a detailed understanding of how carbon-oxygen bonds are formed during the oxidation of alkenes mediated by transition metal oxides. Oxidations of this type form an important class of reactions for the preparation of commodity chemicals and the synthesis of fine chemicals.