PeroBase: A Biological Database for Peromyscus

9807881项目涉及Permyscus(鹿、小鼠和相关物种)生物数据库的开发和实施阶段。在整个北美，Permyscus属的小鼠数量极其丰富，并被广泛用于纯研究和应用研究。Permyscus常用的研究领域包括生态学、遗传学、系统学、进化、行为学、生理学、新陈代谢、寄生虫学、流行病学和毒理学。目前，虽然已经发表了3500多篇期刊文章，数百名研究人员目前在他们的研究中使用Permyscus，但对于这一重要的有机体群体，还没有全面的数据库。设想的数据库虽然包括遗传学，但预计将包含与这些啮齿动物生物学的许多方面有关的广泛信息。因此，这个数据库将与目前可用的几个哺乳动物基因组数据库有很大不同。在1998-2001年期间，我们打算全面开发并在线提供三个组成部分：系统学和进化论、遗传学和神经生物学和行为学。此外，还将提供该属的全面参考书目。长期目标是在五年内使该数据库的大约八到九个主题组成部分保持最新，并随时可在互联网上查阅。五年后，该数据库将独立于国家科学基金会数据库项目的支持进行维护。

9807881Project involves development and implementation phases of a biological database for Peromyscus (deer mice and allied species). Mice of the genus Peromyscus are extremely abundant throughout North America and are widely used in pure and applied research. Research areas in which Peromyscus is commonly used includes ecology, genetics, systematics, evolution, behavior, physiology, metabolism, parasitology, epidemiology, and toxicology. Currently, there is no comprehensive database for this significant group of organisms, although more than 3500 journal articles have been published and several hundred investigators currently use Peromyscus in their research. The database envisioned, although including genetics, is expected to contain a broad range of information concerning many aspects of the biology of these rodents. This database, therefore, will differ substantially from the several mammalian genomic databases currently available. During the period 1998-2001 we intend to fully develop and have on-line three components: Systematics and Evolution, Genetics, and Neurobiology and Behavior. Additionally, a comprehensive bibliography for the genus will be accessible. The long-range objective is to have about eight or nine topical components of the database up to date and readily accessible on the internet within five years. After five years the database will be maintained independently of NSF database program support.