A Database for Peromyscus: Planning Phase

该项目将计划开发一个关于Permyscus属(鹿鼠和55个近缘物种)的生物数据库。在北美，Permyscus属的小鼠数量极其丰富，并被广泛用于纯研究和应用研究。Permyscus常用的研究领域包括生态学、遗传学、系统学、进化论、行为学、生理学、新陈代谢、寄生虫学、流行病学和毒理学。目前还没有关于这一重要生物群的全面数据库，尽管已发表了3500多篇期刊文章，数百名研究人员目前在他们的研究中使用了霉菌素。设想的数据库虽然包括遗传学，但预计将包含与这些啮齿动物生物学的许多方面有关的广泛信息。因此，这个数据库将与目前可访问的几个哺乳动物基因组数据库有很大不同。长期目标是使数据库的大约八到九个专题部分保持最新状态，并可在因特网上随时查阅。Permyscus数据库(PDB)将通过南卡罗来纳大学哥伦比亚分校计算机科学系和Permyscus基因股票中心生物科学系开发和运行。随着规划的进展，其他机构可能会参与进来。现有的几个独立数据库将并入整个数据库。

This project will plan the development of a biological database for the genus Peromyscus (deer mice and 55 allied species). Mice of the genus Peromyscus are extremely abundant throughout North America and are widely used in pure and applied research. Research areas in which Peromyscus is commonly used includes ecology, genetics, systematics, evolution, behavior, physiology, metabolism, parasitology, epidemiology, and toxicology. Currently there is no comprehensive database for this significant group of organisms, although more than 3500 journal articles have been published and several hundred investigators currently use peromyscines in their research. The database envisioned, although including genetics, is expected to contain a broad range of information concerning many aspects of the biology of these rodents. This database, therefore, will differ substantially from the several mammalian genomic databases currently accessible. The long-range objective is to have about eight or nine topical components of the database up to date and readily accessible on the Internet. The Peromyscus Data Base (PDB) will be developed and operated through the Department of Computer Science and the Department of Biological Sciences, Peromyscus Genetic Stock Center, of the University of South Carolina at Columbia. Other institutions may become involved as planning progresses. Several existing free- standing databases will be incorporated into the overall database.