Beta-Cyclodextrin Reaction Cavities-Solid State Reactions- from Disordered Crystals to Added Insight into Reaction - Mechanisms

拟议的研究涉及的有机客体分子在β-环糊精主机的光解机理研究。 反应速率和产物将使用X射线晶体学，固态NMR和GC/MS的组合来确定。有了这个新的奖项，有机和大分子化学计划支持博士的合作研究。内布拉斯加大学林肯分校的哈比森。 该研究的重点是了解决定在固态下形成的产物分布的因素，当分子在溶液中吸收紫外线时，已知会发生反应，暴露于固体基质中β-环糊精空腔中的辐射。 这项工作有望为有机反应如何在固体中发生以及它们与溶液中的反应有何不同提供重要的见解。 它还应该为研究生和本科生提供有价值的化学培训。

The proposed research involves mechanistic studies of the photolysis of organic guest molecules in beta-cyclodextrin hosts. Reaction rates and products will be determined using a combination of x-ray crystallography, solid-state NMR, and GC/MS.With this New award, the Organic and Macromolecular Chemistry Program supports the collaborative research of Drs. John J. Stezowski and Gerard S. Harbison at the University of Nebraska-Lincoln. The research focuses on understanding the factors which determine the distribution of products formed in the solid state when molecules, known to react when they absorb ultraviolet light in solution, are exposed to radiation in a beta-cyclodextrin cavity in a solid matrix. The work is expected to provide important insights into how organic reactions take place in solids, and how they differ from reactions in solution. It should also provide valuable chemical training for both graduate and undergraduate students.