Mechanistic Investigations of Group 14 Cation Radical Reactions

有了这个优先奖，有机和高分子化学计划支持约瑟夫Dinnocenzo博士在罗切斯特大学化学系的继续研究。 研究的重点是在含有亲核试剂的溶液中，含第14族元素（Si，Ge，Sn和Pb）的有机金属自由基阳离子的碎裂机制。 结合动力学和立体化学实验来区分协同和逐步加成/消除机制，建议的研究涉及带正电荷的奇电子物种的裂解反应的基础研究，其中C-M键，M是硅，锗，锡或铅。 这些结果将提供深入了解这些第14族阳离子自由基中间体的结构，反应活性和反应机理，并可能是广泛的有机和物理化学家的兴趣。 这种类型的中间体可能用于有机合成，并且可能涉及固态材料如硅光致抗蚀剂的形成。 这项工作将为有关人员提供良好的培训，其中有两名妇女。

With this Prior award, the Organic and Macromolecular Chemistry Program supports the continuing research of Dr. Joseph Dinnocenzo in the Department of Chemistry of the University of Rochester. The research focuses on the mechanisms of fragmentation of organometallic radical cations containing Group 14 elements (Si, Ge, Sn, and Pb) in solutions containing nucleophiles. A combination of kinetic and stereochemical experiments will be used to distinguish between concerted and stepwise addition/elimination mechanisms.The proposed research involves fundamental studies of fragmentation reactions of positively charged, odd-electron species containing C-M bonds, where M is silicon, germanium, tin or lead. The results will provide insights into the structures, reactivities, and reaction mechanisms of these Group 14 cation radical intermediates, and are likely to be of broad interest to organic and physical chemists. Intermediates of this type are likely to be useful for organic synthesis, and may be involved in the formation of solid state materials such as silicon photoresists. The work will provide excellent training for the personnel involved, two of whom are women.