SBIR Phase I: Expert Agents Assisted Access and Utilization of the Web-Based Biology Workbench

9860066拟议的研究工作将解决目前严重限制生物数据库和信息服务器的可用性和易用性的制约因素。拟议的原型将提供主要生物数据库和分析工具的无缝集成。虽然第一阶段的工作将集中在与蛋白质结构有关的数据库和工具上，但将开发的框架将在许多其他领域得到广泛应用。该框架将包括关于有效利用这种无缝访问不同数据库和工具的多路径学习模块。将纳入以相关案例研究为特色的有指导的利用之旅，使有经验的研究人员全面了解新兴生物信息学领域的能力，以及如何将这些工具整合到传统的“湿”实验室中。将开发和销售与蛋白质结构相关的信息服务器的光盘集成的“引导发现和有效利用”系统。

9860066 The proposed research effort will address current constraints that severely limit the usability and ease of use of biological databases and information servers. The proposed prototype will provide seamless integration of major biological databases and analytical tools. While the Phase I effort will focus on Protein structure related databases and tools, the framework to be developed will find extentive applications in many other fields. The framework will include multi-path learning modules on effective utilization of such a seamless access to diverse databases and tools. Guided utilization tours, featuring relevant case-study examples will be incorporated to provide experienced researchers with a comprehensive understanding of the capabilities of the emerging field of bioinformatics and how such tools may be integrated into traditional "wet" laboratories. CD-ROM integrated "guided discovery and effective utilization" systems for Protein structure related information servers will be developed and marketed.