Phase Transfer Catalysis in Environmentally Benign Supercritical Fluids

建议标题：NTE：环境友好的超临界流体中的相转移催化建议编号：CTS-0086808首席研究员：Charles Eckert研究所：佐治亚理工学院本项目的目标是研究用于超临界流体的相转移催化剂(PTCs)。将进行全氟化PTCs的合成，并进行一系列工业上有用的反应。建议的反应包括置换反应、醚合成、聚合反应和烷基化反应。用超临界二氧化碳取代有机溶剂将对环境产生积极影响。PI计划演示催化剂属性与结构的调整，重点是相分布和活性。该项目代表了化学家和化学工程师之间的多学科合作，以实施一项涉及在安全、廉价、无毒的超临界二氧化碳中进行PTC反应的新技术。反应的化学反应将与下游分离一起进行工程设计，以实现工艺优势和经济效益。PTC目前是一项重要的工业技术，可用于在两种或两种以上的反应物之间进行通常不相容的反应。通过PTC合成了大量的化学产品，提高反应动力学和选择性的新方法可能会产生巨大的经济影响。

AbstractProposal Title: NTE: Phase Transfer Catalysis in Environmentally Benign Supercritical FluidsProposal Number: CTS-0086808Principal Investigator: Charles EckertInstitution: Georgia Institute of TechnologyThe goal of this project is to study phase-transfer catalysts (PTCs) for supercritical fluid applications. Synthesis of perfluorinated PTCs will be carried out, and a series of industrially useful reactions will be performed. Proposed reactions include displacement reactions, ether syntheses, polymerization reactions, and alkylations. The replacement of organic solvents with supercritical carbon dioxide will have a positive environmental impact. The PIs plan to demonstrate the tuning of catalyst properties with structure, focusing on phase distribution and activity. This project represents a multidisciplinary collaboration between chemists and chemical engineers to implement a novel technology involving PTC reactions in safe, cheap, nontoxic supercritical carbon dioxide. The chemistry of the reactions will be engineered with the downstream separations to achieve both process advantages and economic benefits. PTC is currently an important industrial technology, useful for carrying out reactions between two or more reactants that would normally be immiscible. Numerous chemical products are synthesized through PTC, and novel methods for enhancing reaction kinetics and selectivity may have a large economic impact.