The Genetic Architecture of Honey Bee Sucrose Response Thresholds

蜜蜂蔗糖反应阈值的遗传结构。小佩奇这个项目的长期目标是更好地了解行为的变化。 行为是一个人的遗传组成、发展和环境的结果。 观察到的个体之间的行为差异可能是这些因素中任何一个的结果，或者是它们中任何一个或全部的交互组合。 对于任何生物体行为变异的根本原因，我们所知相对较少。 蜜蜂提供了一个独特的机会来研究行为变异，因为它们的行为是刻板的和众所周知的，它们生活在社会群体中，它们经历与年龄相关的行为变化，它们具有非常高的遗传重组率，这有助于它们基因的遗传图谱，并且已经进行了许多关于它们行为的遗传研究。对于这项提议，将构建一个详细的遗传图谱，以绘制与感官性状（糖和水的感知）相关的主要基因。 已经清楚地表明，这种特性与工蜂觅食方面的重要行为“决定”相关。 一个详细的图谱将提供一个假设的测试，即先前绘制的花粉囤积行为（在巢中储存多余的花粉）的相同基因也会影响感官知觉。 它还将识别与感官知觉相关的新基因，并将更好地理解基因如何相互作用和影响行为。 最后，将开发一套接近映射基因的遗传标记，这些标记可用于影响行为的基因和环境相互作用的未来研究，并用于这种自然变化的行为特征的人群研究。

The genetic architecture of honey bee sucrose response thresholdsRobert E. Page, Jr. The long term objective of this project is to better understand variation in behavior. Behavior is a consequence of the genetic makeup, development, and environment of an individual. Observed differences in behavior between individuals can be a consequence of any of these factors, or the interactive combination of any or all of them. There is relatively little known about the underlying causes of variation in behavior for any organism. Honey bees afford a unique opportunity to study behavioral variation because their behavior is stereotypic and well known, they live in social groups, they undergo age related changes in behavior, they have very high rates of genetic recombination that facilitate the genetic mapping of their genes, and many genetic studies of their behavior have been performed. For this proposal, a detailed genetic map will be constructed in order to map major genes associated with a sensory trait, the perception of sugar and water. It has been clearly demonstrated that this trait correlates with important behavioral "decisions" of worker honey bees with respect to foraging. A detailed map will provide a test of the hypothesis that the same genes previously mapped for pollen hoarding behavior (the storing of surplus pollen in the nest) also effect sensory perception. It will also identify new genes associated with sensory perception and will lead to a better understanding of how genes interact and affect behavior. Finally, sets of genetic markers will be developed that are close to the mapped genes that can be used in future studies of gene and environment interactions that affect the behavior, and for use in population studies of this naturally varying behavioral trait.