Acqusition of a New 500 MHz NMR Spectrometer

有了化学研究仪器和设施(CRIF)计划的这一奖项，新汉普郡大学化学系将获得一台500 MHz核磁共振光谱仪。这台设备将使研究人员能够开展以下研究：a)表征C60与聚并苯和四氮杂环的新加合物；b)多胺及其衍生物的表征和动态核磁共振研究，包括具有很强诊断显像剂和抗艾滋病毒药物潜力的化合物；c)开发一种新型的锌卡宾扩链反应，它将有助于将酮亚甲基异构体作为组合文库的一部分；以及d)由杂化配体形成的超分子簇的研究。核磁共振波谱是化学家用来解释分子结构的最有力的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱是必不可少的。这些核磁共振研究的结果将对材料化学、生物技术和纳米技术等多个领域产生影响。

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at the University of New Hampshire will acquire a 500 MHz NMR Spectrometer. This equipment will enable researchers to carry out studies on a) characterization of new cycloadducts of C60 with polyacenes and tetrazines; b) characterization and dynamic NMR studies of polyamines and derivatives, including compounds with strong potential as diagnostic imaging agents and anti-HIV agents; c) development of a novel zinc carbenoid chain extension reaction that will facilitate the inclusion of ketomethylene isosteres as part of combinatorial libraries; and d) studies of supramolecular clusters formed from hybrid ligands. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in a number of areas including materials chemistry, biotechnology and nanotechnology.