Chemical Sensors Based on Imprinted Polymer Nanoparticles

0097409 Tepper这项研究致力于开发一种新的微型传感技术，该技术基于化学敏感和高选择性的聚合物纳米颗粒与微型制造的换能器接口。这些颗粒采用超临界流体聚合物加工、紫外光固化和分子印迹的独特组合，由高度网络化的单分散聚合物纳米颗粒组成，印迹具有对特定分子物种的高选择性。提出的研究项目的主要目标是开发和演示所提出的传感器的性能参数。这将通过开发原型并通过实验验证包括化学敏感性、选择性、响应时间和可逆性在内的关键性能标准来实现。如果成功，建议的传感器将在野外便携式仪器中提供无与伦比的性能水平。建议的传感器技术的应用包括环境表征、医疗诊断、过程控制、智能家电和军事监视。印迹聚合物纳米颗粒的其他应用包括层析、特殊分离和过滤。***

0097409 Tepper This research focuses on the development of a new miniature sensing technology based on chemically sensitive and highly selective polymer nanoparticles interfaced with a microfabricated transduction device. The particles are produced using a unique combination of supercritical fluid polymer processing, UV curing and molecular imprinting and consist of highly networked, monodisperse polymer nanoparticles imprinted for high selectivity to a specific molecular species. The main objective of the proposed research project is to develop and demonstrate the performance parameters of the proposed sensor. This will be accomplished by developing a prototype and experimentally verifying key performance criteria including chemical sensitivity, selectivity, response time and reversibility. If successful, the proposed sensor would provide an unsurpassed level of performance in a field portable instrument. Applications of the proposed sensor technology include environmental characterization, medical diagnostics, process control, intelligent appliances, and military surveillance. Additional applications for the imprinted polymer nanoparticles include chromotography, specialty separations and filtering. ***