U.S.-Portugal-Switzerland Cooperative Research: Multiscale Models of Blood Flow in the Cerebral Vasculature

0104680罗伯逊美国-意大利-葡萄牙-瑞士的合作研究涉及匹兹堡大学的Anne Robertson和瑞士洛桑联邦理工学院的Alfio Quarteroni以及葡萄牙里斯本上级技术学院的Adelia塞凯拉。 意大利米兰理工大学的Alessandro Veneziani是Quarteroni教授小组的成员，也将参加。多国和多学科团队建议开发人体血管系统中血流的多尺度模型。具体而言，他们计划从数学、数值分析和物理/工程的角度对多尺度模型进行评估。意大利小组将提供牛顿和非牛顿流体的数学流体力学方面的专业知识;瑞士小组将提供有限和谱元方法、人体心血管系统血流的数值模拟、流体-结构相互作用和多尺度建模方面的专业知识; PI具有连续介质力学方面的经验，包括流体力学和数值模拟; 2葡萄牙小组具有流体力学数学分析和数值方法方面的知识。合作的目标是开发一种更复杂的数值模拟工具，使用更新的流体动力学模型，可用于理解和评估血管疾病的临床治疗策略。

0104680RobertsonThis three-year award for U.S.-Italian-Portuguese-Swiss cooperative research involves Anne Robertson of the University of Pittsburgh and Alfio Quarteroni of the Ecole Polytechnique Federale de Lausanne, Switzerland and Adelia Sequeira of the Instituto Superior Tecnico in Lisbon, Portugal. Alessandro Veneziani of the Politecnico di Milano in Italy is a member of Professor Quarteroni's group and will also participate. The multinational and multidisciplinary team proposes to develop multiscale models of blood flow in the human vascular system. Specifically, they plan to evaluate multiscale models from the perspective of mathematics, numerical analysis, and physics/engineering.The Italian group brings expertise in mathematical fluid mechanics for Newtonian and non-Newtonian fluids; the Swiss group will contribute expertise in finite and spectral element methods, numerical simulation of blood flow in human cardiovascular systems, fluid-structure interactions, and multiscale modeling; the PI has experience in continuum mechanics, including fluid mechanics and numerical simulation; and the Portuguese group is knowledgeable in mathematical analysis and numerical methods in fluid mechanics. The goal of the collaboration is to develop a more sophisticated numerical simulation tool, using a newer fluid dynamics model, that can be used for understanding and evaluating clinical treatment strategies for vascular disease.