SBIR PHASE I: Heterogenized Homogeneous Catalysts based on Polymer-Supported N-Heterocyclic Carbenes

这个小企业创新研究第一阶段项目将研究非均相（负载型）钯N-杂环卡宾（NHC）催化剂的技术和商业可行性。 均相钯催化反应是形成碳-碳和碳-杂原子键的有效方法，例如Heck和Suzuki反应。然而，它们在精细化学品制造中的商业应用受到与均相催化剂相关的低效率的负担，主要是回收和再循环，这可以通过开发负载型催化剂来消除。 成功的研究和开发将产生简化反应后处理、减少废物流和通过回收降低成本的商业产品。

This Small Business Innovation Research Phase I project will research technical and commercial feasibility of heterogenized homogeneous (supported) palladium N-heterocyclic carbene (NHC) catalysts. Homogeneous palladium-catalyzed reactions are powerful methods for carbon-carbon and carbon-hetero atom bond formations, such as Heck and Suzuki reactions. However, their commercial adoption in fine chemical manufacture has been burdened by the inefficiencies associated with homogeneous catalysts, primarily recovery and recycling, which could be eliminated by the development of supported catalysts. Successful research and development would result in commercial products that would simplify post-reaction processing, reduced waste streams and reduction in costs via recycling.