Acquisition of a Pulsed Fourier Transform Electron Paramagnetic Resonance Spectrometer

在化学研究仪器和设施(CRIF)计划的这一奖项下，西北大学化学系将获得一台脉冲傅立叶变换电子顺磁共振(EPR)光谱仪。新仪器将支持下列领域的研究：a)使用时间分辨EPR光谱(Wasielewski)绘制固定距离光生自由基离子对内的电子耦合图(Wasielewski)；b)直接观察双链DNA中鸟嘌呤正离子自由基的情况(Lewis)；c)时间分辨在能量转换化学中的应用：发现并确定光活性界面上的电子陷阱(HUPP)；d)蛋白质络合物内电子转移的时间分辨EPR研究(Hoffman)；e)钴(II)取代锌结合结构域的EPR研究(Godwin)；以及f)单胺氧化酶的EPR研究(Silverman)。电子顺磁共振(EPR)光谱仪是一种用于获取分子的分子和电子结构信息的仪器。它还可以用来获得有关自由基寿命的信息，这些自由基通常是启动肿瘤生长和/或各种化学反应所必需的。这些研究将在许多领域产生影响，特别是光功能材料化学和生物物理化学。

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at Northwestern University will acquire a Pulsed Fourier Transform Electron Paramagnetic Resonance (EPR) Spectrometer. The new instrument will support research in the following areas: a) mapping electronic coupling within photogenerated radical ion pairs at fixed distances using time-resolved EPR spectroscopy (Wasielewski); b) direct observation of guanine cation radical in duplex DNA (Lewis); c) time-resolved applications in energy conversion chemistry: finding and identifying electron traps at photo-active interfaces (Hupp); d) time-resolved EPR of electron transfer within protein complexes (Hoffman); e) EPR studies on cobalt (II)-substituted zinc-binding domains (Godwin); and f) EPR studies of monoamine oxidase (Silverman). An electron paramagnetic resonance (EPR) spectrometer is an instrument used to obtain information about the molecular and electronic structure of molecules. It may also be used to obtain information about the lifetimes of free radicals which are often essential for the initiation of tumor growth and/or a variety of chemical reactions. These studies will have an impact in a number of areas, in particular the chemistry of photofunctional materials and biophysical chemistry.