ADVANCE Fellow: The Role of Electrostatics in Nucleic Acid Structure and Function

这个先进的研究员奖，通过化学和物理的部门，将支持马西娅O。佛罗里达州立大学分子生物物理研究所的Fenley博士说。 该项目将使用理论和计算方法来阐明静电对核酸结构和功能的作用。具体而言，离子气氛和静电势的模型结构的三链核酸将使用数值凝聚和泊松-玻尔兹曼方法进行检查。这些计算可以阐明各种离子对核酸结构、构象变化和相变的作用。该奖项由NSF ADVANCE计划提供支持。高级方案的总体使命是通过增加妇女在学术科学和工程职业中的代表性和地位，增加妇女在科学和工程劳动力中的参与。

This ADVANCE Fellows award, through the Divisions of Chemistry and Physics, will support the research of Marcia O. Fenley in the Institute of Molecular Biophysics at Florida State University. The project will use theoretical and computational approaches to elucidate the role of electrostatics on the structure and function of nucleic acids. Specifically, the ion atmosphere and electrostatic potential of model structures of triple-stranded nucleic acids will be examined using numerical counterion condensation and Poisson-Boltzmann methods. These calculations may elucidate the role of various ions on nucleic acid structure, conformation changes and phase transitions. This award is supported through the NSF ADVANCE Program. The overall mission of the ADVANCE Program is to increase the participation of women in the scientific and engineering workforce through the increased representation and advancement of women in academic science and engineering careers.