RUI: Image Aquisition and Analysis Facility for Faculty-Student Research

三一大学生物系的David Ribble博士获得了一笔赠款，用于资助最先进的图像采集和分析仪器和软件。该设备将被安置在图像采集和分析中心，这是一个多用户研究设施，将提高三一大学生物系所有教师和本科生的研究能力。三一大学将改造现有的实验室，为该中心提供场地，并将分担设备和软件的费用。为了满足这个多样化研究社区的需求，该中心将包含设备和软件来获取、存储和分析适合分子生物学、细胞生物学、生理学、生态学和进化研究的图像。为了满足这些需求，将购买以下设备：凝胶文件系统；具有反褶积功能的荧光显微镜，数码相机，计算机和支持软件。图像采集和分析中心将大大提高教师和学生的研究能力，加强生物系内各种研究小组的活动。每一个小组都将大量使用这个新设施。这些正在进行的研究项目包括研究以下主题：内质网分泌蛋白mrna选择性失稳的机制排卵期卵巢基因表达的变化centenum红螺旋菌gtp结合蛋白对光系统产生的调控肠上皮细胞细胞旁紧密连接的通透性大鼠表皮细胞对射频辐射的反应一夫一妻制的进化和哺乳动物的保护蚜虫的群居和群居寄生这些设备是否支持教师和学生正在进行的研究活动？拟议设备的灵敏度、分辨率和分析能力将为三一学院目前无法实现的研究计划和方向提供机会。此外，使用这一共享设施将有助于在生物系内不同分支学科之间开展合作研究项目。

Abstract A grant has been awarded to Dr. David Ribble of the Biology Department at Trinity University to fund state of the art image acquisition and analysis instrumentation and software. This equipment will be housed in the Center for Image Acquisition and Analysis, a multi-user research facility that will enhance the research capabilities of all faculty and undergraduate students in the Department of Biology at Trinity University. Trinity University will remodel an existing laboratory to provide a site for this Center and will share in the cost of the equipment and software. To satisfy the needs of this diverse research community, the Center will contain equipment and software to acquire, store, and analyze images appropriate to research studies in molecular biology, cellular biology, physiology, ecology, and evolution. To meet these needs, the following items of equipment will be purchased: a gel documentation system; a fluorescence microscope with deconvolution capabilities, digital cameras, computers, and support software. The Center for Image Acquisition and Analysis will significantly increase faculty and student research capabilities, enhancing the activities of the varied research groups within the Department of Biology. Each of these groups will make intensive use of this new facility. These ongoing research projects include the study of the following topics: The mechanisms for selective destabilization of secretory protein mRNAs at the ER Changes in ovarian gene expression during ovulation Regulation of photosystem production by a putative GTP-binding protein in Rhodospirillum centenum Paracellular permeability of tight junctions in intestinal epithelial cells Rat epidermal cell responses to radiofrequency radiation Evolution of monogamy and conservation of mammals Sociality and social parasitism in galling aphids Not only will this equipment support the ongoing research activities of faculty and students; the sensitivity, resolution, and analysis capabilities of the proposed equipment will provide opportunities for research initiatives and directions not currently possible at Trinity. Furthermore, use of this shared facility will help develop collaborative research projects between the diverse sub-disciplines within the Department of Biology.