Intermolecular and Intramolecular Electron Transfer Reactions

有了这个更新提案，有机和大分子化学计划支持威斯康星大学麦迪逊分校化学系斯蒂芬·尼尔森教授正在进行的工作。Nelsen教授的这项工作概述了各种桥接供体-受体化合物（主要是双肼）中电子转移的几个机制研究。尼尔森教授试图继续他在分子内电子转移的机制和能量方面的工作，使用合成，测量和建模方法，专注于六个定义明确的问题。在这个建议中，他已经确定了电子转移领域中最重要的技术和概念问题，这个建议的成功将对解决这些问题大有帮助。在物理有机化学中，化学反应性的研究一直是电子对转移反应的研究领域。然而，单电子转移引起了越来越多的关注，因为人们对外圈反应和更复杂的过程感兴趣，其中电子转移与键断裂或键形成相结合。就机理和反应性而言，这个领域还有很多有待发现的东西，纳尔逊教授的工作将对这些发现大有帮助。电子转移反应在化学和生物学中都是非常重要的，例如，在光合作用和呼吸作用这两个非常重要的生命过程中都发现了电子转移反应。总的来说，整个科学和社会自然会从尼尔森教授在化学研究这一重要领域为年轻科学家提供的培训中受益。通过这个奖项，化学学部的有机和大分子化学项目支持了威斯康星大学麦迪逊分校化学系斯蒂芬·尼尔森教授的研究活动。尼尔森教授在理解电子转移反应方面一直处于世界领先地位。除了回答物理有机化学中的一些基本问题外，博士后和研究生将在重要化学反应的合成，测量和建模方面接受独特的培训。

With this renewal proposal the Organic and Macromolecular Chemistry Program supports the on- going work of Professor Stephen Nelsen in the Department of Chemistry at the University of Wisconsin- Madison. This work by Professor Nelsen outlines several mechanistic studies of electron transfer in various bridged donor-acceptor compounds, primarily bis-hydrazines. Professor Nelsen seeks to continue his work on the mechanistic and energetic aspects of intramolecular electronic transfer using a synthetic, measurement, and modeling approach to focus on six well-defined questions. In this proposal he has identified the most important technical and conceptual problems in the electron transfer field, and success with this proposal will go a long way toward solving these problems. Investigation of chemical reactivity in physical organic chemistry has long been the realm of electron pair transfer reactions. However, single electron transfer has attracted increasing attention where the interest has been concerned with outer- sphere reactions and with more complex processes where electron transfer is coupled with bond breaking or bond formation. There is much to be discovered in this field in terms of mechanisms and reactivity and Professor Nelson's work will go a long way toward making these discoveries. Electron transfer reactions are very important in both chemistry and biology, and are found, for example, in photosynthesis and respiration, two very important life processes. In general, science as a whole and society will naturally benefit from the training that Professor Nelsen will provide younger scientists in this important area of chemical research.With this Award, the Organic and Macromolecular Chemistry Program of the Division of Chemistry supports the research activities of Professor Stephen Nelsen in the Department of Chemistry at the University of Wisconsin- Madison. Professor Nelsen continues to be a world leader in understanding electron transfer reactions. In addition to answering some fundamental questions in physical organic chemistry, post-doctoral and graduate students will receive unique training in synthesis, measurement, and modeling of important chemical reactions.