NER: Towards Self-Assembled Metallodendrimers for Multi-Anion Sensing

这项研究的重点是制备金属树枝状纳米传感器结构，该结构在阴离子存在的情况下对特定的荧光变化敏感。构建块将由能够与阴离子结合的受体部分和通过荧光PI连接的低聚物连接的配体组成。金属-配体的配位作用将驱动纳米树枝状结构的组装。选择配体和金属模板形成具有金属-配体电荷转移状态的荧光三(喹啉)Al3+、双(喹啉)锌(2+)或三(1，10-邻菲咯啉)OS2+配合物。由此得到的金属树枝状大分子将形成一种高度荧光的结构，在阴离子物质存在的情况下，这种结构很容易受到光学性质的变化的影响，这种阴离子物质可以与结构中包含的受体结合在一起。有了这项纳米级：探索性研究(NER)奖，有机和高分子化学计划以及特殊项目化学办公室将支持鲍灵格林大学化学系的Pavel Anzenbacher博士的研究。Anzenbacher教授将专注于开发和表征用于多分析环境中化学传感的自组装光学纳米传感器。这项研究可能会对用于传感极低浓度的多种阴离子底物的材料的生产产生重要而广泛的影响，如无机阴离子、化肥和药物。

The focus of this research involves the preparation of metallodendritic nanosensor architectures susceptible to a specific change in fluorescence in the presence of anions. The building blocks will be composed of a receptor moiety capable of anion binding, and a ligand, connected by a fluorescent pi-conjugated oligomer. The metal-ligand coordination will drive the assembly of nanosized dendritic architectures. The ligand and metal template are selected to form fluorescent tris(quinolato)AL3+, bis(quinolato)Zn2+ or tris(1,10-phenanthroline)Os2+ complexes exhibiting metal-to-ligand charge transfer states. The resulting metallodendrimers would form a highly fluorescent architecture that would be susceptible to a change in optical properties in the presence of anionic substances that can bind to the receptors contained in the architecture.With this Nanoscale: Exploratory Research (NER) award, the Organic and Macromolecular Chemistry Program and the Chemistry Office of Special Projects are supporting the research of Dr. Pavel Anzenbacher of the Department of Chemistry at Bowling Green University. Professor Anzenbacher will focus his work on the development and characterization of self-assembled optical nanosensors for chemical sensing in multianalyte environments. The research could have an important broader impact on the production of materials for sensing multiple anionic substrates such as inorganic anions, fertilizers, and pharmaceuticals at very low concentrations