Functional Interlocked Macromolecules and Interpenetrating Supramolecular Polymers

这项研究的重点是自下而上地制造机械互锁聚合物，首先是预组织步骤，其中单体通过非共价力聚集在一起，然后是将单体以共价或共价和机械方式连接在一起的固定步骤，以形成聚合物。超分子和机械互锁聚合物的构建依赖于二次双烷基铵离子中心和至少具有[24]冠-8结构的冠醚之间发生的氢键和其他相互作用，以相互穿透的方式将识别单元聚集在一起。光化学和动态共价化学将被用来帮助形成互锁聚合物。在聚合步骤中使用可逆键的形成将允许生产热力学上最稳定的聚合物。凭借这一奖项，有机和高分子化学计划支持加州大学洛杉矶分校化学和生物化学系的J.Fraser Stoddart博士的研究。斯托达特博士将专注于使用非共价合成来创建超分子聚合物，并利用超分子辅助进行共价合成来构建机械互锁聚合物。从更广泛的意义上讲，了解这些聚合物的形成将导致新的和独特的聚合物材料的发展，并将对含有动态共价键和机械键的纳米材料的制备有深入的了解。该项目还为本科生、研究生和研究生的跨学科培训提供了一个极好的场所。

The focus of this research involves the bottom-up fabrication of mechanically interlocked polymers starting with a preorganization step, where monomers are brought together by noncovalent forces, followed by a "fixing" step that links the monomers covalently or covalently and mechanically, to form the polymers. The construction of both the supramolecular and mechanically interlocked polymers depends on the hydrogen bonding and other interactions that occur between a secondary dialkylammonium ion center and a crown ether with at least [24] crown-8 constitution to bring the recognition units together in an interpenetrating manner. Both photochemistry and dynamic covalent chemistry will be used to assist in the formation of the interlocked polymers. The use of reversible bond formation in the polymerization step will allow for the production of the most thermodynamically stable polymer.With this award, the Organic and Macromolecular Chemistry Program is supporting the research of Dr. J. Fraser Stoddart of the Department of Chemistry and Biochemistry at the University of California-Los Angeles. Dr. Stoddart will focus his work on using noncovalent synthesis to create supramolecular polymers and employ supramolecular assistance to covalent synthesis to construct mechanically interlocked polymers. In a broader sense, understanding the formation of these polymers will lead to the development of new and unique polymeric materials and will give insight into the fabrication of nanoscale materials containing dynamic covalent and mechanical bonds. The project also provides an excellent venue for the interdisciplinary training of undergraduate, graduate and postgraduate students.