A Tabletop Ultracentrifuge for Biology

该奖项为科罗拉多州立大学生物系购买高速台式超离心机提供部分支持。该仪器将允许：(1)快速分离，(2)同时分离许多小体积样品，(3)分析级梯度离心。该设备将支持植物生物学、细胞与发育生物学、转运生理学和植物修复等领域的许多研究项目。超离心的应用包括：亚细胞区室中转运蛋白、受体和调节因子的定位；发展运输分析；细胞骨架元素的共沉淀法；多体分离；rna -蛋白复合物的分离；清除无细胞提取物；和核酸的梯度离心。生命科学教育和研究是科罗拉多州立大学整体学术活动的核心，这些设备也将增强学生在REU项目和高级细胞生物学课程中的经验。

This award provides partial support for the purchase of a high-speed tabletop ultracentrifuge in the Biology Department at Colorado State University. The instrument will allow: (1) fast separations, (2) the separation of many small volume samples simultaneously, and (3) analytical scale gradient centrifugation. A number of research projects in the areas of Plant Biology, Cell and Developmental Biology, Transport Physiology, and Phytoremediation will be supported by this equipment. Applications for the ultracentrifuge include: localization of transporters, receptors and regulators in sub-cellular compartments; development of transport assays; cosedimentation assays for cytoskeletal elements; separation of polysomal fractions; isolation of RNA-protein complexes; clearance of cell free extracts; and gradient centrifugation of nucleic acids. Life science education and research are at the core of the overall scholarly activity at Colorado State University, and the equipment will also enhance the experience of students both in REU programs and in upper division cell biology classes.