U.S.- Chile Cooperative Research: Anthropogenic Influences on the Environmental Dissemination of Bacteria and Bacterial Genes

0405419辛格这项美国-智利奖将为明尼苏达大学双子城分校的兰德尔·辛格博士与智利康塞普西翁大学的Gerardo E. Gonzalez-Rocha博士合作提供支持。本项目的部分支持来自环境中的生物复杂性计划。这些项目将研究人为因素对细菌和细菌基因在环境中传播的影响。这个项目的重点是大肠杆菌在复杂的自然环境中分散的生态过程。他们还将研究那些被认为会增加这些细菌的多样性、抗菌素耐药性和毒性的因素。通过在农村环境中开展一项基于生态系统的研究，他们将评估特定人为变化、其他环境和社会学参数与大肠杆菌多样性、耐药性和毒力变化之间的关系。这项活动将增加我们对人为环境变化如何在相关和重要的生态环境中促进新病原体出现的理解。它将有助于发展将微生物学、流行病学和生态学数据与传播/扩散模型联系起来的方法。

0405419SingerThis U.S.-Chile award will provide support for Dr. Randall Singer, University of Minnesota-Twin Cities, to collaborate with Dr. Gerardo E. Gonzalez-Rocha, Universidad de Concepcion in Chile. Partial support for this project comes from the Biocomplexity in the Environment (BE) Program.The PIs will work on anthropogenic influences on the environmental dissemination of bacteria and bacterial genes. The focus of this project is on the ecological processes by which E. coli disperse into complex natural environments. They will also look at factors that are hypothesized to increase the diversity, antimicrobial resistance, and virulence of these bacteria. Through an ecosystem-based study in a rural environment, they will assess the relationships among specific anthropogenic changes, other environmental and sociological parameters, and changes in the diversity, resistance and virulence of E. coli. This activity will increase our understanding of how anthropogenic environmental changes facilitate the emergence of novel pathogens in a relevant and important ecological setting. It will aid in the development of methods for linking microbiological, epidemiological and ecological data into a dissemination/dispersal model.