STTR Phase I: Benign Thin Film Composite Particles for Protection from UVA/UVB - Rays

这个小型企业技术转移（STTR）一期项目将开发复合TiO2/ZnO（二氧化钛/氧化锌）颗粒，上面覆盖着Al2O3纳米层，可以对UVA/UVB射线进行良性保护。二氧化钛（TiO2）对UVB射线有很好的保护作用。氧化锌（ZnO）非常有效地防止uva射线。通过新的原子层沉积（ALD）薄膜技术制造复合颗粒，可以合成具有双重功效的复合颗粒。在这项工作的第一个方面，ZnO将通过ALD沉积在纳米级TiO2颗粒上。在本工作的第二个方面，将在亚微米大小的球形二氧化硅（SiO2）颗粒表面制备TiO2和ZnO的纳米层膜。大的衬底SiO2将为“UVA/UVB防晒剂”提供足够大的粒径，以防止人体皮肤毛孔堵塞。在这两种情况下，复合颗粒将被氧化铝（Al2O3）纳米层覆盖，这将使这些颗粒在非水配方中易于分散。Al2O3纳米层还可以防止活性TiO2/ZnO与皮肤直接接触，从而保护皮肤免受潜在的紫外线热活化反应的影响。我们会测试这些微粒的UVA/UVB透过率，并计算防晒系数（SPF）。该技术更广泛的影响可能是能够生产具有设计的电、磁、光学、机械、流变特性的超细颗粒，该技术可能对微电子、国防、硬金属、化妆品、药物输送、高能材料和聚合物/陶瓷纳米复合材料产生重大的商业影响。

This Small Business Technology Transfer (STTR) Phase I project will develop composite TiO2/ZnO (Titania /Zinc Oxide) particles capped with an Al2O3 nanolayer for benign protection from UVA/UVB - rays. Titania (TiO2) provides excellent protection against UVB - rays. Zinc oxide (ZnO) protects against UVA-rays very efficiently. The manufacture of composite particles via novel Atomic Layer Deposition (ALD) thin film technology allows for the synthesis of composite particles with dual effectiveness. In the first aspect of this work, ZnO will be deposited on nanosized TiO2 particles by ALD. In the second aspect of this work, nanolaminated films of TiO2 and ZnO will be prepared on the surface of submicron sized spherical silica (SiO2) particles. The large substrate SiO2 will provide a particle size for the "UVA/UVB sun blockers" that will be large enough to prevent pore blockage in human skin. In both instances, the composite particles will be capped with an alumina (Al2O3) nanolayer that will allow easy dispersion of these particles in non-aqueous formulations. The Al2O3 nanolayer will also prevent direct contact of the active TiO2/ZnO with the skin, thus protecting the skin from potential UV-hot activated reactions. The particles will be tested for UVA/UVB transmittance and Sun Protection Factors (SPF) will be calculated.The broader impacts of the technology could be the ability to produce ultrafine particles with designed electrical, magnetic, optical, mechanical, rheological properties, this technology could have significant commercial impact on microelectronics, defense, hard-metals, cosmetics, drug delivery, energetic materials, and polymer/ceramic nanocomposites.