The Southern California Genotyping Consortium

该奖项为获得基于脑珠的基因分型仪器提供了部分支持。该仪器将允许高通量、低成本的单核苷酸多态性（snp）基因分型，由几个南加州机构的用户组成的联盟，包括：加州大学洛杉矶分校、加州大学欧文分校、加州大学圣地亚哥分校和南加州大学。该系统将用于全基因组关联研究和对众多种群和不同生物体中选定基因组区域的深入研究。将受益于此次获得的项目包括：(1)确定连锁不平衡图谱是否可以作为一种非常有效的方法来理解植物变异的分子基础，(2)开发改良栽培作物的一般方法，(3)了解蝴蝶的翅膀眼斑模式，(4)解剖桡足类动物的合子后分离，(5)描述经济上重要的牡蛎，以及(6)哺乳动物保护工作。

This award provides partial support for the acquisition of a bead-based genotyping instrument. The instrument will permit high throughput, low cost genotyping of single nucleotide polymorphisms (SNPs) by a consortium of users at several Southern California institutions, including: UCLA, UC Irvine, UC San Diego, and the University of Southern California. The system will be used for genome-wide association studies and intensive study of selected genome regions in numerous populations and different organisms. Projects that will benefit from the acquisition include: (1) determining if linkage disequilibrium mapping can be used as an extremely efficient method for understanding the molecular basis of variation in plants, (2) development of general methods for improving cultivated crops, (3) understanding wing eyespot patterning in butterflies, (4) dissecting postzygotic isolation in copepods, (5) characterizing economically important oysters, and (6) mammalian conservation efforts.