F05 Symposium L "Mechanical Behavior of Biological and Biomimetic Materials; Boston, MA; November 28 - December 2, 2005

本次研讨会的主要目标是联合两个传统上不同的社区内的研究人员，以促进材料和生物力学行为的界面的探索。该论坛将通过将生物材料和生物力学的科学家和工程师与医学和牙科的临床医生联系起来，促进应用于生物和仿生材料的建模和实验技术的进步。 生物组织和仿生材料通常表现出从纳米尺度到宏观尺度的结构和组成变化。这些天然材料，沿着被设计成模仿它们的组成和结构的仿生材料，由于组成和整体分级结构的局部变化而表现出复杂的机械响应。这些材料中的许多是粘弹性的，其中它们的时间依赖性行为难以在多个尺度下适当地量化和建模。生理条件的模拟需要复杂的测试环境。因此，先进的实验技术和多尺度建模方法至关重要。因此，本次研讨会旨在进一步应用现有的方法和开发新技术，用于生物和仿生材料的研究。 由于天然组织在体内执行特定的机械功能，因此了解天然材料的机械响应以开发替代生物材料以恢复失去的机械功能是至关重要的。力学行为还可以提供对生物材料的超微结构和组织的洞察，这反过来可以提供关于结构-功能关系的独特信息，并导致非生物应用工程材料开发的新进展。本次研讨会将促进传统材料科学工作者和强调生物科学工作的研究人员之间的讨论和新关系的形成。

The primary goal of this symposium is to unite researchers within two traditionally distinct communities to promote exploration of the interface of mechanical behavior of materials and biology. This forum will facilitate advancements in modeling and experimental techniques as applied to biological and biomimetic materials by connecting scientists and engineers in biomaterials and biomechanics with clinicians in medicine and dentistry. Biological tissues and biomimetic materials generally exhibit structural and compositional variations from the nano- to the macro-scale. These natural materials, along with biomimetic materials designed to imitate their composition and structure, exhibit complicated mechanical responses due to local variations in composition and overall hierarchical structure. Many of these materials are viscoelastic, where their time-dependent behavior is difficult to appropriately quantify and model at multiple scales. Simulation of physiological conditions necessitates complicated testing environments. Advanced experimental techniques and multiscale modeling approaches are thus essential. Therefore, this symposium seeks to further the application of existing methods and the development of new techniques for the study of biological and biomimetic materials. Since natural tissues perform specific mechanical functions in vivo, it is critical that a native material's mechanical response is understood in order to develop replacement biomaterials to restore lost mechanical functions. Mechanical behavior can also provide insight into the ultrastructure and organization of biological materials, which in return can provide unique information regarding structure-function relations and lead to new advances in the development of engineered materials for non-biological applications. This symposium will facilitate discussion and the formation of new relationships between those working in traditional materials science and researchers whose work emphasizes the biological sciences.