nnGordon Conference: 2006 Tetrapyrroles, Chemistry and Biology of Gordon Research Conference

该奖项为第21届戈登研究会议（GRC）提供了支持，该会议将于2006年7月23日至28日在RI新港的Salve Regina大学举行，主题是四吡啶的化学和生物学。会议将为来自不同科学学科、对四吡咯化合物的化学和生物学有共同兴趣的新老研究者提供一个交流思想的论坛。四吡咯具有多种作用，如催化氧化还原反应、收集光能、激活、输送和感应双原子气体（如氧气、一氧化碳和一氧化氮）。此外，它们是必需营养素（如维生素B12），并经常通过转录和翻译作用（如血红素）调节信号系统和蛋白质表达。讨论主题包括：光感应四吡咯，四吡咯合成的生化和细胞方面，四吡咯合成的新方面，复杂生物过程中的血红素，四吡咯化学：纳米结构和人工血红素蛋白，四吡咯作为调节剂，健康和疾病中血红素代谢的酶，四吡咯运输。更广泛的影响：本次GRC展示和讨论的四吡咯研究的跨学科性质和范围广泛，通过推进对许多基础科学过程和应用的发现和理解，将研究和教育结合起来。此外，通过计划的海报会议和青年调查人员的口头报告来促进教学和培训，从而产生一种促进初级和高级调查人员之间互动的氛围。会议扩大了在四吡啶科学领域未被充分代表的群体的参与，包括相当比例的妇女、其他少数群体成员和初级研究人员（研究生和博士后研究员）在GRC会议计划中作为演讲者和讨论领袖。对整个社会的潜在好处包括从天然和合成四吡啶的化学和光化学性质衍生出许多实际应用的发展，如生物传感器、作物产量提高、农药、催化剂、荧光探针和太阳能转换。

This award provides support for the 21st Gordon Research Conference (GRC) on the Chemistry and Biology of Tetrapyrroles at Salve Regina University, Newport, RI to be held July 23-28, 2006. The conference will provide a forum for the exchange of ideas between established and new investigators from a wide variety of scientific disciplines with common interests in the chemistry and biology of tetrapyrrole compounds. Tetrapyrroles have diverse roles, such as catalyzing redox reactions, harvesting light energy, and activating, delivering and sensing diatomic gases (e.g. oxygen, carbon monoxide and nitric oxide). In addition, they are essential nutrients (e.g. vitamin B12) and often act as regulators of signaling systems and protein expression, via transcriptional and translational effects (e.g. heme). Discussion topics include: LIGHT SENSING TETRAPYRROLES, BIOCHEMICAL & CELLULAR ASPECTS OF TETRAPYRROLE SYNTHESIS, NOVEL ASPECTS OF TETRAPYRROLE SYNTHESIS, HEME IN COMPLEX BIOLOGICAL PROCESSES, TETRAPYRROLE CHEMISTRY: NANOSTRUCTURES AND ARTIFICIAL HEME-PROTEINS, TETRAPYRROLES AS REGULATORS, ENZYMES OF HEME METABOLISM IN HEALTH & DISEASE, and TETRAPYRROLE TRAFFICKING. Broader impacts: The inter-disciplinary nature and broad range of tetrapyrrole research presented and discussed at this GRC integrate research and education by advancing discovery and understanding of many fundamental scientific processes and applications. Furthermore, teaching and training are promoted via planned poster sessions and oral presentations of young investigators, which generate an atmosphere that fosters interactions between junior and senior investigators. The meeting broadens the participation of underrepresented groups in the area of tetrapyrrole science by including a significant proportion of women, members of other minority groups, and junior investigators (graduate students and post-doctoral fellows) in the GRC conference program as speakers and discussion leaders. The potential benefits to society at large include the development of many practical applications derived from the chemical and photochemical properties of natural and synthetic tetrapyrroles such as biosensors, crop yield improvement, pesticides, catalysts, fluorescent probes and solar energy conversion.