SBIR Phase I: Immunological Tools for Trimetasphere Fullerenes

这个小型企业创新研究(SBIR)第一阶段项目将致力于碳质纳米材料抗体的生产、表征和应用。具体地说，这些是三金属内面体富勒烯，三元非球体(TMS)。该项目将开发新的纳米材料，并生产基于单克隆和多克隆抗TMS抗体的免疫探针和亲和力矩阵。所开发的免疫学工具将在TMS作为对照和治疗剂的开发和使用中发挥重要作用。这些工具的使用将扩大对这些创新的TMS试剂的化学、细胞介导的反应和药代动力学的科学和技术理解。

This Small Business Innovative Research (SBIR) Phase I project will address the production, characterization and application of antibodies to carbonaceous nanomaterials. Specifically, these are the trimetallic endohedral fullerene, Trimetaspheres (TMS). The project will develop the novel nanomaterials and produce immunoprobes and affinity matrices based on monoclonal and polyclonal anti-TMS antibodies. These will be used to evaluate the effects of the TMS as contrasting and therapeutic agents.The immunological tools developed will play an important role in the development and use of the TMS as contrasting and therapeutic agents. The use of these tools will expand the scientific and technological understanding of the chemistry, cell-mediated responses and the pharmacokinetics of these innovative TMS reagents.