GRK 1721: Integrated Analysis of Macromolecular Complexes and Hybrid Methods in Genome Biology

分子生物学的研究向着复杂性分析的方向发展。我们以独特和有竞争力的培训和研究网络GRK1721来满足这一发展。我们的博士研究人员破译了基因组生物学中“复杂大分子系统”的结构和机制。GRK1721旨在通过整合生命科学中的多尺度方法，连接结构蛋白科学中先前分离的学科，并在混合方法的新兴领域培养科学家，来解决大分子复合物的结构-功能系统分析的下一个水平。我们的研究和培训计划将使跨学科的博士项目能够解决基因组生物学中瞬态和模块化大分子复合物的结构，机制和分子调控。我们成功的以学分为基础的培训和指导计划，包括必修和选修活动，允许博士研究人员根据他们的个人需求和项目要求定制课程。核心部分将是高级方法研讨会，以促进跨学科研究和特定项目混合方法的开发。我们相信GRK1721将有助于培养能够成功应对未来结构基因组生物学挑战的新一代科学家。

Research in molecular biology moves towards the analysis of complexity. We meet this development with the unique and competitive training and research network GRK1721. Our doctoral researchers decipher the structures and mechanisms of "complex macromolecular systems" in genome biology. GRK1721 is designed to tackle the next level of structure-functionsystem analysis of macromolecular complexes by integrating multi-scale approaches in life science, bridging previously separated disciplines in structural protein science, and training scientists in the emerging field of hybrid methods. Our research and training program will enable cross-disciplinary doctoral projects to address the structure, mechanism and molecular regulation of both transient and modular macromolecular complexes in genome biology. Our successful credit-based training and mentoring program with required and optional activities allows the doctoral researchers to tailor the curriculum according to their individual needs and project requirements. A core part will be advanced methods workshops that facilitate cross-disciplinary research and development of project specific hybrid approaches. We believe that the GRK1721 will help to train a new generation of scientists that are capable to successfully tackle future challenges in structural genome biology.