Shared Genome Database Informatics and Cyber Infrastructure

印第安纳大学获得了一笔赠款，用于开发集成的共享数据库工具，例如那些在协作通用模型生物数据库（GMOD）项目的保护伞下建立的工具。完全组装、分析和比较这些基因组的软件工具是可用的，但使用它们的能力仅限于那些拥有广泛计算资源和工程人才的人。在这个项目中，正在开发用于现有和新兴模式生物数据库的方法，这些方法将解决基因组数据库访问需求和用于比较分析的中间件。共享网络基础设施的有效使用，如nsf赞助的TeraGrid和其他网格系统，是通过数据网格方法来解决的，这些方法划分了大型基因组数据库集，以便有效地使用网格系统。BIOSCI/Bionet，一个生物新闻和讨论网络，即将进入其为生命科学界服务的第三个十年。该项目将维护和改进几个模式生物群落的Bionet新闻，以及分子方法，生物软件，微生物学，蛋白质，植物生物学和其他领域。该项目管理的生物镜像项目用于分发大型基因组和生物学数据库，并为有效的基因组数据库分析提供基础设施。该项目改善了所有公民获得生命科学知识的总体途径。它有助于广泛的科学家、学生和公众的教育，与生物学和信息学教学和研究的国家和行业目标保持一致。该项目是美国和全球生物信息学基础设施的一个组成部分，并改善了与亚太、非洲、欧洲和西半球国家的伙伴关系。BIOSCI/Bionet新闻、IUBio档案和Bio-Mirror项目将继续数十年来为世界社会提供公众获取生物学信息的记录。

Indiana University is awarded a grant to develop integrated, shared database tools, such as those built under the umbrella of the collaborative Generic Model Organism Database (GMOD) project. Software tools to fully assembly, analyze and compare these genomes are available, but the ability to employ them is limited to those with extensive computational resources and engineering talent. In this project, methods are being developed for use by existing and emerging model organism databases that will address genome database access needs and middleware for comparative analyses. Effective use of shared cyberinfrastructure, such as NSF-sponsored TeraGrid and other Grid systems, is addressed with data grid methods that partition large genome database sets for effective use of Grid systems. BIOSCI/Bionet, a network of biology news and discussion, is approaching its third decade of service to the life sciences community. This project will maintain and improve Bionet news for several model organism communities, and areas of molecular methods, bio-software, microbiology, proteins, plant biology and others. The Bio-mirror project for distribution of large genomic and biology databanks is administered under this project, and provides infrastructure for effective genome database analyses. This project improves overall access to life sciences knowledge for all citizens. It aids the education of a broad spectrum of scientists, students and the general public, consistent with national and industry goals of teaching and research in biology and informatics. The project is a component of the infrastructure of bioinformatics in the US and worldwide, and improves partnerships with Asian-Pacific, African, European and western hemisphere nations. BIOSCI/Bionet news, IUBio Archive and Bio-Mirror projects will continue a multi-decade record of serving the world community with public access to biology information.