CAREER: Spectroscopic and Electrochemical Studies of Nanoparticle Size, Shape, and Surface Chemistry

在分析和表面化学项目的支持下，明尼苏达大学化学系的海恩斯教授和她的同事们正在研究纳米材料对细胞机械功能的影响。利用电化学和光谱探针研究了纳米粒子的大小、形状、组成和表面化学对模型细胞系统功能的影响。碳纤维微电极安培法和细胞功能的钙离子成像将用于检测纳米材料的细胞毒性。这一职业奖结合了纳米材料领域的研究生培训，重点是技术写作和科学成果的展示。利用电化学和光谱探测器，海恩斯教授和她的同事们正在研究贵金属和聚合物纳米颗粒对模型细胞系功能的影响。这些材料的摄取作为大小、形状、组成和化学的函数将被用来理解这些材料的细胞毒性。纳米材料在消费品和一般环境中的应用越来越多，这表明需要更好地了解这些材料对细胞功能的影响。这一职业奖将技术写作和演示培训与研究生的研究培训结合在一起。

AbstractCHE-0645041Haynes/MinnesotaWith the support of the Analytical and Surface Chemistry Program, Professor Haynes and her colleagues in the Department of Chemistry at the University of Minnesota are examining the effects of nanoscale materials on the function of cellular machinery. The effects of nanoparticle size, shape, composition and surface chemistry on the function of model cellular systems are investigated using electrochemical and spectroscopic probes. Carbon fiber microelectrode amperometry, and calcium ion imaging of cell function will be used to assay cytotoxicity of the nanoparticle materials. This Career award integrates graduate training in the area of nanomaterials with emphasis on technical writing and presentation of scientific results. Using electrochemical and spectroscopic probes, Professor Haynes and her coworkers are examining the effects of noble metal and polymeric nanoparticles on the function of model cell lines. Uptake of these materials as a function of size, shape, composition and chemistry will be used to understand cytotoxicity of these materials. Growing applications of nanomaterials in consumer products and in the general environment indicate a need for a better understanding of the effects of these materials on cellular function. This Career award integrates training in technical writing and presentation with the research training of graduate students.