Collaborative Research: Genomics as the Foundation of a New Undergraduate Curriculum

生物科学（61）亚利桑那州立大学与梅萨社区学院和西雅图太平洋大学合作，正在实施一种以基因组学为重点的、基于研究的方法来教授核心生物科学课程。该项目的智力价值在于，通过将所有课程整合到一个涉及多个学校和教育水平的大型、高度协作的基因组学研究项目中，所涉及的课程将教授关键概念和技能。该计划是跨学科的，包括细菌基因组计划的课程，在几个学期的课程中开始，完成和发表。课程作业本身就是一个研究项目，学生学习所有必要的技能和概念，因为项目的每个新阶段都需要新的专业知识水平。许多学生还会发起个人研究项目来跟进他们的课堂作业。这种教学方法是由PI Slater和他的合作者Goodner博士在对农杆菌进行基因组测序时开发的（Goodner等人，Science）。294:2323，后者的出版物有超过12名本科生作为共同作者)，并且此后由Hiram学院的Goodner博士和他的同事非常成功地实施（Goodner等人，ASM News. 69:584）。该方法包括集成实验室机器人组件，并扩展与梅萨社区学院的持续合作。该提案的更广泛影响包括改善大学与当地社区学院区之间的合作，改善STEM领域学生的招聘和保留，重点关注少数民族的招聘，本科生对科学文献的重大贡献，以及具有丰富知识，技术和沟通技能的毕业生。正在制作详细的材料，并将其传达给其他机构的教育工作者。

Biological Sciences (61)Arizona State University in collaboration with Mesa Community College and Seattle Pacific University is implementing a genomics-focused, research-based approach for teaching the core biological science classes. The intellectual merit of this project is that the courses involved teach critical concepts and skills by integrating all courses into a large, highly collaborative genomics research project that involves multiple schools and educational levels. The program is interdisciplinary, consisting of courses in which bacterial genome projects are initiated, completed, and published over the course of several semesters. The course work is itself a research project, and the students learn all of the necessary skills and concepts as each new stage of the project requires a new level of expertise. Many students also initiate individual research projects to follow-up their classroom work. This method of teaching was developed by PI Slater and his collaborator Dr. Goodner when they sequenced the Agrobacterium tumefaciens genome (Goodner et al.,Science. 294:2323, the latter publication had over a dozen undergraduates as coauthors) and has since been very successfully implemented by Dr. Goodner and his colleagues at Hiram College (Goodner et al., ASM News. 69:584). The approach includes integration of a laboratory robotics component and extends an ongoing collaboration with Mesa Community College.The broader impacts of this proposal include improved articulation of efforts between the university and a local community college district, improved recruitment and retention of students in STEM fields, a focused effort on minority recruitment, significant contributions by undergraduate students to the scientific literature, and graduates with a rich set of intellectual, technical and communications skills. Detailed materials are being produced and communicated to educators from other institutions.