New statistical methods for identifying micro-ribonucleic acid (miRNA) regulatory networks
New statistical methods for identifying micro-ribonucleic acid (miRNA) regulatory networks
批准号:
FT0991918
负责人:
Prof Jean Yang
金额:
$45.48万
依托单位:
依托单位国家:
澳大利亚
项目类别:
ARC Future Fellowships
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-02-25 至 2016-03-17
中文摘要
理解基因调控网络对于理解基础生物系统至关重要。这些网络对于发现与许多疾病的诊断和管理有关的基本机制具有重要意义。本研究将通过多元协方差估计和多元分类技术,为识别调控微核糖核酸模块以及了解它们在基因调控网络中的关系提供新的统计方法。我的研究结果应该使研究人员能够更好地理解生物系统的基本规律,从而改善人类健康、医学和生物学的研究成果。
英文摘要
Understanding gene regulatory networks is critical in the understanding of fundamental biological systems. These networks have important implications for the discovery of fundamental mechanisms relating to the diagnosis and management of many illnesses. This research will provide new statistical methods to identify regulatory micro-ribonucleic acid modules and to understand their relationship in gene regulatory networks through multiple covariance estimation and multivariate classification techniques. My results should enable researchers to better understand the regulation underlying biological systems, leading to improved human health, medical and biological research outcomes.
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会议论文
Prognosis based network-type feature extraction for complex biological data
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批准号:DP170100654
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项目类别:Discovery Projects
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资助金额:$24.81万
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财政年份:2017
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负责人:Prof Jean Yang
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依托单位:
Statistical bioinformatics for network based prognostic and precision therapy in complex disease
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批准号:nhmrc : GNT1111338
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项目类别:Career Development Fellowships
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资助金额:$46.37万
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财政年份:2016
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负责人:Prof Jean Yang
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依托单位:
Statistical bioinformatics for network based prognostic and precision therapy in complex disease
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批准号:nhmrc : 1111338
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项目类别:Career Development Fellowships
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资助金额:$31.9万
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财政年份:2016
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负责人:Prof Jean Yang
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依托单位:
Vertically integrated statistical modelling in multi-layered omics studies
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批准号:DP130100488
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项目类别:Discovery Projects
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资助金额:$27.72万
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财政年份:2013
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负责人:Prof Jean Yang
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依托单位:
Statistical and computational methods using a multiscale approach for protein identification and quantification
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批准号:DP0984267
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项目类别:Discovery Projects
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资助金额:$18.02万
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财政年份:2009
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负责人:Prof Jean Yang
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依托单位:
Statistical methods and tools for integrative microarray analysis
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批准号:DP0770395
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项目类别:Discovery Projects
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资助金额:$17.69万
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财政年份:2007
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负责人:Prof Jean Yang
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依托单位:
国内基金
海外基金
基于随机网络演算的无线机会调度算法研究
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批准号:60702009
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项目类别:青年科学基金项目
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资助金额:24.0万元
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批准年份:2007
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负责人:雷蕾
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依托单位: