MRI: Acquisition of UPLC-TQMS and MALDI-TOFMS
MRI: Acquisition of UPLC-TQMS and MALDI-TOFMS
批准号:
0923095
负责人:
Kenneth Carter
金额:
$57.8万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-08-01 至 2013-07-31
中文摘要
该奖项是根据2009年美国复苏和再投资法案(公法111-5)资助的。通过这项来自主要研究仪器(MRI)项目的奖励,中阿肯色大学化学系将获得一台液相色谱三重四极杆质谱仪和一台用于非色谱材料和原位分析的飞行时间质谱仪。研究项目包括:固体有机载体上镍配合物的反应性、光谱和传感特性;光敏性氨基酸自由基前体;高氟化树状大分子的合成及其氧传递性能噻唑烷二酮存在时类视黄醇代谢的研究细菌培养基中脂质分析及其分类潜力蒸发金属薄膜和金属粉末上芳香纳米膜的激光解吸研究古代洞穴壁画中有机结合剂的表征。质谱法(MS)是一种分析技术,用于鉴定样品的化学成分,并通过测量样品中分子成分的质量来确定其纯度。液相色谱法是一种先于质谱分析的分离技术。它将混合物分离成几种化学成分,然后由质谱仪进行分析和鉴定。质谱法是应用最广泛的分析仪器技术之一。正因为如此,对于本科生来说,在参与上述研究项目时,接受现代仪器技术的培训是很重要的。
英文摘要
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).With this award from the Major Research Instrumentation (MRI) program, the Department of Chemistry at the University of Central Arkansas will acquire a liquid chromatography triple quadrupole mass spectrometer and a time-of-flight mass spectrometer for non-chromatographable materials and for in situ analysis. A variety of research projects will be investigated including: Reactivity, Spectroscopic, and Sensing Properties of Nickel Complexes on Solid Organic Supports; Photolabile Amino Acid Radical Precursors; Synthesis and Oxygen Transport Properties of Highly Fluorinated Dendrimers; Retinoid Metabolism in the Presence of Thiazolidinediones; Analysis of Lipids from Bacterial Growth Media and their Potential in Taxonomy; Laser Desorption Studies of Aromatic Nanofilms Adsorbed on Evaporated Metal Films and Metal Powders; and the Characterization of Organic Binders in Ancient Cave Paints.Mass spectrometry (MS) is an analytical technique used to identify the chemical composition of a sample and to determine its purity by measuring the mass of the molecular constituents in the sample. Liquid chromatography is a separation technique that precedes the mass spectrometry analysis. It separates a mixture into its several constituent chemicals which are then analyzed and identified by the mass spectrometer. Mass spectrometry is one of the most widely used analytical instrumentation techniques. Because of this, it is important for undergraduate students to be trained in the technique on modern instrumentation as they participate in research projects such as those mentioned above.
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