MRI: Acquisition of a Roche Genome Sequencer Titanium System for Studies of Microbial Communities

这项主要研究仪器（MRI）奖资助了罗氏基因组测序仪FLX钛系统的收购，该系统允许加州大学戴维斯分校（UC）进行大规模高通量“下一代”DNA测序。该系统将成为微生物多样性测序设施的核心，该设施将成为加州大学戴维斯分校微生物多样性研究和教育的活跃中心，并与外部合作者合作。微生物多样性是加州大学戴维斯分校许多关键研究领域的基础，包括农业、葡萄栽培、微生物学、进化、生态学、生物能源、生物修复、营养和植物、动物和人类的发病机制。罗氏基因组测序器FLX钛系统将建立在这些优势上，通过在校园内几十个实验室进行革命性的研究，促进研究人员调查微生物群落不同方面的富有成效的互动，并招募新的研究人员到该领域。此外，该系统将通过加州大学戴维斯分校基因组中心的一个核心设施提供给校园和该地区的其他人使用。该系统将激发和塑造多样化的教育、培训和推广活动。此外，微生物多样性测序设施将在收集和有意义地使用大量DNA序列数据方面培训本科生、研究生和博士后。最后，这些仪器将与外部本科教育机构合作使用，为他们提供设备和数据的访问权限，这些设备和数据可作为课程和研究活动的一部分。通过使用这一设备开展的研究、教育和外联活动将在项目网站http://microbialdiversity.ucdavis.edu上进行总结。

This Major Research Instrumentation (MRI) award funds the acquisition of a Roche Genome Sequencer FLX Titanium System that allows massively high throughput "Next Generation" DNA sequencing at the University of California (UC) Davis. This system will form the core of a Microbial Diversity Sequencing Facility that will serve as an active center for both research and education in microbial diversity across the UC Davis Campus and with outside collaborators. Microbial diversity is fundamental to many key fields of research at UC Davis including agriculture, viticulture, microbiology, evolution, ecology, bioenergy, bioremediation, nutrition, and pathogenesis in plants, animals, and humans. The Roche Genome Sequencer FLX Titanium System will build on these strengths by revolutionizing the research in dozens of labs across campus, facilitating productive interaction between researchers investigating different aspects of microbial communities, and recruiting new researchers to this field. In addition, the system will be made available to others on campus and in the area through a core facility in the UC Davis Genome Center. The system will invigorate and shape diverse educational, training, and outreach activities. Furthermore, the Microbial Diversity Sequencing Facility will function in training undergraduates, graduate students, and post-docs in the gathering and meaningful use of massive amounts of DNA sequence data. Finally, the instrumentation will be used in partnerships with outside undergraduate educational institutions to provide them with access both to the equipment and to data that can be used as part of courses and research activities.Research, educational and outreach activities produced through the use of this equipment will be summarized on a project web site at http://microbialdiversity.ucdavis.edu.